Biostatistics/Bioinformatics Unit
David Rossell
Core Facility Manager
Office Tel : +34 93 40 20217
e-mail : david.rossell
irbbarcelona.org
Background
The mission of the Biostatistics/Bioinformatics Unit is to conduct collaborative research and to provide consultation and quantitative research resources to all IRB Barcelona research groups.
We assist scientists by providing both short and long-term consultancy services in the following areas:
- Experimental design: sample size, study design, planning of statistical methodology
- Data analysis: clinical or biomedical databases, genomics data
- Assistance with statistical methodology in own or others’ research
- Software: help in using software, develop software to meet special data analysis or study design needs
The facility conducts methodological research and develops resources in all of the above-mentioned areas.
For more information contact the manager of the Biostatistics/Bioinformatics Unit at
david.rossell
irbbarcelona.org.
More info
Biostatistics/Bioinformatics Unit
Isolation and in vitro expansion of human colonic stem cells
Jung P, Sato T, Merlos-Suárez A, Barriga FM, Iglesias M, Rossell D, Gallardo MM, Blasco MA, Sancho E, Clevers H, Batlle E.
Nature Medicine, [Epub ahead of print on Sept 4, 2011] (2011)
Tumor-stroma interactions a trademark for metastasis
Morales M, Planet E, Arnal-Estape A, Pavlovic M, Tarragona M, Gomis RR
Breast, 3 (20), s50-s55 (2011)
The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse.
Merlos-Suárez A, Barriga FM, Jung P, Iglesias M, Céspedes MV, Rossell D, Sevillano M, Hernando-Momblona X, da Silva-Diz V, Muñoz P, Clevers H, Sancho E, Mangues R, Batlle E
Cell Stem Cell, 8 (5), 511-524 (2011)
Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph
Casabonne D, Reina O, Benavente Y, Becker N, Maynadie M, Foretova L, Cocco P, Gonzalez-Neira A, Nieters A, Boffetta P, Middeldorp JM and de Sanjose S
Haematological, 96 (2), 323-327 (2011)
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
Janic A, Mendizabal L, Llamazares S, Rossell D, Gonzalez C.
Science, 330 (6012) (2010)
Non-Local prior densities for default Bayesian hypothesis tests
Johnson VE and Rossell D
J Roy Statist Soc B, 72, 143-170 (2010)
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain R, Cubells L, Bori-Sanz T, Alvarez-Medina R, Rossell D, Martí E and de Pouplana LR
Nucleic Acids Research (2009)
GaGa: a parsimonious and flexible model for diferential expression analysis
Rossell D
Ann Appl Statist, 3 (3), 1035-1051 (2009)
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain R, Cubells L, Bori-Sanz T, Alvarez-Medina R, Rossell D, Martí E and de Pouplana LR
Nucleic Acids Research (2009)
Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and relative-of-WOC (ROW) to regulate gene expression
Font-Burgada J, Rossell D, Auer H and Azorín F
Genes Dev, 22 (21), 3007-3023 (2008)
Semi-parametric differential expression analysis via partial mixture estimation
Rossell D, Guerra R and Scott C
Stat Appl Genet Mol Biol, 15 (7) (2008)
Bayes factors based on test statistics under order restrictions
Rossell D, Baladandayuthapani V and Johnson VE
Bayesian evaluation of informative hypotheses in psychology. Hoijtink H, Klugkist I, Boelen P (Eds.).Springer (2008)