Chemistry & Molecular Pharmacology
The Chemistry and Molecular Pharmacology Programme undertakes interdisciplinary research of excellence at the interface of Chemistry and Biology, by performing a series of key activities related to organic synthesis, conformational analysis and molecular recognition studies.
We synthesize a large variety of bioactive compounds, with special focus on nucleic acids, peptides and proteins, pseudopeptides and peptidomimetics, polyheterocyclic nitrogen-containing systems and five-membered ring compounds. The methodological axes for innovation are: enantioselective synthesis, solid-phase synthesis of libraries of bioactive compounds and multi-component reactions.
From the viewpoints of medicinal chemistry and drug design, the programme focuses on molecular recognition studies. Using a variety of spectroscopic and biophysical methods, these studies examine the interaction of drug candidates with their specific therapeutic targets. Nuclear magnetic resonance, computation and, in the future, mass spectrometry, are the three main tools applied in research into molecular recognition.
Programme coordinatorErnest Giralt
Office Tel: +34 93 40 37125
- Fernando Albericio: Combinatorial Chemistry
- Ernest Giralt: Peptides and Proteins
- Antoni Riera: Asymmetric Synthesis
- Xavier Salvatella: Laboratory of Molecular Biophysics
Senior Research Officer
Office Tel: +34 93 40 37132
Office Tel: +34 93 40 37124