Maria J. Macias: Protein NMR Spectroscopy Laboratory

Maria Jesus Macias

Group Leader
ICREA Research Professor
Office Tel: +34 93 40 37189
Lab Tel: +34 93 403 71 88
e-mail: maria.maciasirbbarcelona.org

Born in Zamora, Spain, in 1964. Degree in Chemistry from the University of Salamanca, Spain (1989). Currently working at the Department of Structural and Computational Biology at the Institute for Research in Biomedicine –IRB Barcelona.

Ph.D. student in the group of Prof. Manuel Grande Benito, Dep. of Organic Chemistry Facultad de Ciencias Químicas, University of Salamanca (1989-1993). Postdoctoral Fellow in the group of Prof. Hartmut Oschkinat, department of structures and biocomputing EMBL, Heidelberg (Germany, 1993-98). Staff-Scientist l EMBL, department of structures and biocomputing EMBL, Heidelberg (Germany 1998-2002). ICREA researcher at the Institute for the Research in Biomedicine –IRB (Since 2002 till present).

Research activity focus on the Structural characterization of biomolecules by Nuclear Magnetic resonance.

A selection of articles:

• Macias, et al. Structure of the pleckstrin homology domain from b-spectrin. Nature 1994; 369, 675-677.
• Macias, M.J. et al. A. Structure of the double stranded RNA-binding domain from E. coli Rnase III (*Joint first authors). EMBO Journal 1995; 14, 3572-3584.
• Macias, M.J., et al. Structure of the WW domain of a kinase-associated protein in complex with a proline-rich peptide. Nature 382 1996; 646-649.
• Macias M.J., et al. Structural analysis of WW domains and design of a WW prototype. Nature Structural Biology 2000; 7(5): 375-9.

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