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"Towards personalized T-cell therapies for solid cancers" - Alena Gros, PhD - Tumor Immunology and Immunotherapy Group - VHIO - Barcelona

19 Mar 21

Speaker: Alena Gros, PhD -  Tumor Immunology and Immunotherapy Group - VHIO - Barcelona

 

Imagen

Presentation

Organizers: IRB Barcelona
Date: Friday 19 March 2021, 12.00h

Host: Lluís Ribas de Pouplana, PhD - IRB Barcelona

 

Biomed Webinar

Open to predoctoral UPF students

If you are interested in participating, please send an email to natalia.molner@irbbarcelona.org 

ABSTRACT

Cancer immunotherapies exploit the immune system to attack cancer. Adoptive cell transfer (ACT), which consists in the administration of large numbers of antitumor T cells, can lead to durable antitumor responses in patients with metastatic melanoma and is currently being investigated for the treatment of solid cancers. T cells mediate specific tumor recognition through the interaction of the T-cell receptor with a peptide derived from a tumor antigen presented by the major histocompatibility complex. In this talk I present the challenges and current efforts to identify the personalized tumor antigens as well as the tumor-reactive TCR repertoire that will contribute to better understand and develop more effective immunotherapies for the treatment of solid cancers.