Publicaciones sobre Investigación

Title

Year

Research Group

Dally proteoglycan mediates the autonomous and nonautonomous effects on tissue growth caused by activation of the PI3K and TOR pathways

Ferreira, A; Milán, M

PLOS BIOLOGY

e1002239 -

2015

Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila

Gottardo, M; Pollarolo, G; Llamazares, S; Reina, J; Riparbelli, MG; Callaini, G; Gonzalez, C

CURRENT BIOLOGY

2319 -

2324

2015

A role for E-cadherin in ensuring cohesive migration of a heterogeneous population of non-epithelial cells

Campbell, K; Casanova, J

Nature Communications

7998 -

2015

Inosine modifications in human tRNAs are incorporated at the precursor tRNA level

Torres, AG; Piñeyro, D; Rodríguez-Escribà, M; Camacho, N; Reina, O; Saint-Léger, A; Filonava, L; Batlle, E; de Pouplana, LR

NUCLEIC ACIDS RESEARCH

5145 -

5157

2015

Structural determinants of Smad function in TGF-β signaling

Macias, MJ; Martin-Malpartida, P; Massagué, J

TRENDS IN BIOCHEMICAL SCIENCES

296 -

308

2015

DDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes

Kessler, R; Tisserand, J; Font-Burgada, J; Reina, O; Coch, L; Attolini, CSO; Garcia-Bassets, I; Azorín, F

Nature Communications

7049 -

2015

Liver glycogen reduces food intake and attenuates obesity in a high-fat diet-fed mouse model

López-Soldado, I; Zafra, D; Duran, J; Adrover, A; Calbó, J; Guinovart, JJ

DIABETES

796 -

807

2015

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Calon, A; Lonardo, E; Berenguer-Llergo, A; Espinet, E; Hernando-Momblona, X; Iglesias, M; Sevillano, M; Palomo-Ponce, S; Tauriello, DVF; Byrom, D; Cortina, C; Morral, C; Barceló, C; Tosi, S; Riera, A; Attolini, CSO; Rossell, D; Sancho, E; Batlle, E

NATURE GENETICS

320 -

U62

2015

Asymmetric intermolecular cobalt-catalyzed pauson-khand reaction using a p-stereogenic bis-phosphane

Orgué, S; León, T; Riera, A; Verdaguer, X

ORGANIC LETTERS

250 -

253

2015

QUIESCENCE Quantitative differences, qualitative outcomes

Pollarolo, G; Gonzalez, C

eLife

e04869 -

2015

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

Pavlovic, M; Arnal-Estapé, A; Rojo, F; Bellmunt, A; Tarragona, M; Guiu, M; Planet, E; Garcia-Albéniz, X; Morales, M; Urosevic, J; Gawrzak, S; Rovira, A; Prat, A; Nonell, L; Lluch, A; Jean-Mairet, J; Coleman, R; Albanell, J; Gomis, RR

JNCI-Journal of the National Cancer Institute

107

djv256 -

djv256

2015

Neutrophils support lung colonization of metastasis-initiating breast cancer cells

Wculek SK, Malanchi I#
(#) Corresponding author

Nature

528(7582):413-7

2015

Hyperactivated endolysosomal trafficking in melanoma

Alonso-Curbelo D, Soengas MS

Oncotarget

2015

RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development

Alonso-Curbelo D, Osterloh L, Cañón E, Calvo TG, Martínez-Herranz R, Karras P, Martínez S, et al, [corr. author] Soengas MS.

Oncotarget

2015

Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH

Urosevic, J; Garcia-Albéniz, X; Planet, E; Real, S; Céspedes, MV; Guiu, M; Fernandez, E; Bellmunt, A; Gawrzak, S; Pavlovic, M; Mangues, R; Dolado, I; Barriga, FM; Nadal, C; Kemeny, N; Batlle, E; Nebreda, AR; Gomis, RR

NATURE CELL BIOLOGY

685 -

2014

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression

Whissell, G; Montagni, E; Martinelli, P; Hernando-Momblona, X; Sevillano, M; Jung, P; Cortina, C; Calon, A; Abuli, A; Castells, A; Castellvi-Bel, S; Nacht, AS; Sancho, E; Attolini, CSO; Vicent, GP; Real, FX; Batlle, E

NATURE CELL BIOLOGY

695 -

2014

Neurons have an active glycogen metabolism that contributes to tolerance to hypoxia

Saez, I; Duran, J; Sinadinos, C; Beltran, A; Yanes, O; Tevy, MF; Martinez-Pons, C; Milan, M; Guinovart, JJ

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

945 -

955

2014

Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements

Zhou, R; Maisuradze, GG; Suñol, D; Todorovski, T; Macias, MJ; Xiao, Y; Scheraga, HA; Czaplewski, C; Liwo, A

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

111

18243 -

18248

2014

The dynamics of microtubule minus ends in the human mitotic spindle

Lecland, N; Lüders, J

NATURE CELL BIOLOGY

770 -

U248

2014

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

Afroz, T; Skrisovska, L; Belloc, E; Guillén-Boixet, J; Méndez, R; Allain, FHT

GENES & DEVELOPMENT

1498 -

1514

2014

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

Morales, M; Arenas, EJ; Urosevic, J; Guiu, M; Fernández, E; Planet, E; Fenwick, RB; Fernández-Ruiz, S; Salvatella, X; Reverter, D; Carracedo, A; Massagué, J; Gomis, RR

EMBO Molecular Medicine

865 -

881

2014

Fenwick, RB; Orellana, L; Esteban-Martín, S; Orozco, M; Salvatella, X

Nature Communications

4070 -

2014

Glycogen accumulation underlies neurodegeneration and autophagy impairment in lafora disease

Duran, J; Gruart, A; García-Rocha, M; Delgado-García, JM; Guinovart, JJ

HUMAN MOLECULAR GENETICS

3147 -

3156

2014

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

Sala, D; Ivanova, S; Plana, N; Ribas, V; Duran, J; Bach, D; Turkseven, S; Laville, M; Vida, H; Karczewska-Kupczewska, M; Kowalska, I; Straczkowski, M; Testar, X; Palacín, M; Sandri, M; Serrano, AL; Zorzano, A

JOURNAL OF CLINICAL INVESTIGATION

124

1914 -

1927

2014

Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival

Gupta, J; Barrantes, ID; Igea, A; Sakellariou, S; Pateras, IS; Gorgoulis, VG; Nebreda, AR

CANCER CELL

484 -

500

2014

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

Rosell, A; Meury, M; Alvarez-Marimon, E; Costa, M; Pérez-Cano, L; Zorzano, A; Fernández-Recio, J; Palacín, M; Fotiadis, D

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

111

2966 -

2971

2014

Metastatic stem cells: Sources, niches, and vital pathways

Oskarsson, T; Batlle, E; Massagué, J

Cell Stem Cell

306 -

321

2014

ChroGPS, a global chromatin positioning system for the functional analysis and visualization of the epigenome

Font-Burgada, J; Reina, O; Rossell, D; Azorín, F

NUCLEIC ACIDS RESEARCH

2126 -

2137

2014

Control of Cdc28 CDK1 by a Stress-Induced lncRNA

Nadal-Ribelles M; Solé C; Xu Z; Steinmetz LM; deNadal E; Posas F

MOLECULAR CELL

549 -

561

2014

Thread insertion of a bis(dipyridophenazine) diruthenium complex into the DNA double helix by the extrusion of at base pairs and cross-linking of DNA duplexes

Boer, DR; Wu, LS; Lincoln, P; Coll, M

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1949 -

1952

2014

Structural basis for DNA binding specificity by the auxin-dependent ARF transcription factors

Boer, DR; Freire-Rios, A; van den Berg, WAM; Saaki, T; Manfield, IW; Kepinski, S; López-Vidrieo, I; Franco-Zorrilla, JM; de Vries, SC; Solano, R; Weijers, D; Coll, M

CELL

156

577 -

589

2014

Specification of leading and trailing cell features during collective migration in the Drosophila trachea

Lebreton, G; Casanova, J

JOURNAL OF CELL SCIENCE

127

465 -

474

2014

MicroRNA-Mediated Regulation of Dp53 in the Drosophila Fat Body Contributes to Metabolic Adaptation to Nutrient Deprivation

Barrio, L; Dekanty, A; Milán, M

Cell Reports

527 -

540

2014

Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

Novoa, EM; Camacho, N; Tor, A; Wilkinson, B; Moss, S; Marín-García, P; Azcárate, IG; Bautista, JM; Mirando, AC; Francklyn, CS; Varon, S; Royo, M; Cortés, A; de Pouplana, LR

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

111

E5508 -

E5517

2014

RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway

Alonso-Curbelo D, Riveiro-Falkenbach E, Pérez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megías D, Cañón E, et al, [corr. author] Soengas MS.

Cancer Cell

2014

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

Winter G.E., Radic B. (#), Mayor-Ruiz C. (#), Blomen V.A., Trefzer C., Kandasamy R.K., Huber K.V.M., Gridling M., Chen D., Klampfl T., Kralovics R., Kubicek S., Fernandez-Capetillo O., Brummelkamp T.R., Superti-Furga G. (# Equal contribution)

Nat Chem Bio

768 -

773

2014

Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK

Pereira, L; Igea, A; Canovas, B; Dolado, I; Nebreda, AR

EMBO Molecular Medicine

1759 -

1774

2013

Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies

Guitart, T; Picchioni, D; Pineyro, D; de Pouplana, LR

NUCLEIC ACIDS RESEARCH

6595 -

6608

2013

On the origin of the selectivity of plasmidic H-NS towards horizontally acquired DNA: Linking H-NS oligomerization and cooperative DNA binding

Fernández-de-Alba, C; Berrow, NS; Garcia-Castellanos, R; García, J; Pons, M

JOURNAL OF MOLECULAR BIOLOGY

425

2347 -

2358

2013

Drosophila melanogaster: A model and a tool to investigate malignancy and identify new therapeutics

Gonzalez, C

NATURE REVIEWS CANCER

172 -

183

2013

Bantam miRNA promotes systemic growth by connecting insulin signaling and ecdysone production

Boulan, L; Martín, D; Milán, M

CURRENT BIOLOGY

473 -

478

2013

SnapShot: P38 MAPK substrates

Trempolec N; Dave-Coll N; Nebreda A

CELL

152

924 -

924.e1

2013

Coordinated control of replication and transcription by a SAPK protects genomic integrity

Duch, Alba; Felipe-Abrio, Irene; Barroso, Sonia; Yaakov, Gilad; Garcia-Rubio, Maria; Aguilera, Andres; de Nadal, Eulalia; Posas, Francesc

NATURE

493

7430

116 -

119

2013

Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts

Januschke, J; Reina, J; Llamazares, S; Bertran, T; Rossi, F; Roig, J; Gonzalez, C

NATURE CELL BIOLOGY

241 -

248

2013

CPEB1 coordinates alternative 3''-UTR formation with translational regulation

Bava, FA; Eliscovich, C; Ferreira, PG; Miñana, B; Ben-Dov, C; Guigó, R; Valcárcel, J; Méndez, R

NATURE

495

7439

121 -

125

2013

The SLC3 and SLC7 families of amino acid transporters

Fotiadis, D; Kanai, Y; Palacín, M

MOLECULAR ASPECTS OF MEDICINE

2-3

139 -

158

2013

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

Muñoz, JP; Ivanova, S; Sánchez-Wandelmer, J; Martínez-Cristóbal, P; Noguera, E; Sancho, A; Díaz-Ramos, A; Hernández-Alvarez, MI; Sebastián, D; Mauvezin, C; Palacín, M; Zorzano, A

EMBO JOURNAL

2348 -

2361

2013

Synthesis and application of beta-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group

Aiguabella, N; del Pozo, C; Verdaguer, X; Fustero, S; Riera, A

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5355 -

5359

2013