Chemistry and Molecular PharmacologyLaboratory of Molecular Biophysics

Laboratory of Molecular Biophysics

A high resolution description of the structure and dynamics of proteins is a very useful tool to study the properties and the function of these important biomacromolecules and, most importantly, to understand how changes in sequence or environment can lead to disease. The research work carried out at the Laboratory of Molecular Biophysics aims, on the one hand, at developing methods to probe the fluctuations of the structure of proteins by combining experimental data and molecular simulations and, on the other hand, at understanding how changes in such motions relate to the molecular recognition of proteins, to their function and disease.

Fenwick RB, Orellana L, Esteban-Martín S, Orozco M and Salvatella X.
Nat Commun, 5 4070 (2014)
Candotti M, Esteban-Martín S, Salvatella X and Orozco M.
P Natl Acad Sci Usa, 110 (15), 5933-8 (2013)
Fenwick RB, Esteban-Martín S, Richter B, Lee D, Walter KF, Milovanovic D, Becker S, Lakomek NA, Griesinger C and Salvatella X.
J Am Chem Soc, 133 (27), 10336-9 (2011)
Mossuto MF, Bolognesi B, Guixer B, Dhulesia A, Agostini F, Kumita JR, Tartaglia GG, Dumoulin M, Dobson CM and Salvatella X.
Angew Chem Int Edit, 50 (31), 7048-51 (2011)
Esteban-Martín S, Fenwick RB and Salvatella X.
J Am Chem Soc, 132 (13), 4626-32 (2010)
Mossuto MF, Dhulesia A, Devlin G, Frare E, Kumita JR, de Laureto PP, Dumoulin M, Fontana A, Dobson CM and Salvatella X.
J Mol Biol, 402 (5), 783-96 (2010)

Group news & mentions

29 Feb 2016

Xavier Salvatella (Barcelona, ​​1972), a biophysicist at the Institute for Research in Biomedicine (IRB Barcelona), is the focus of

14 Jul 2015

The newspaper “El Periódico de Catalunya” has echoed the award ceremony of the 77 grants given by the “Obra Social La Caixa” foundation to support doctoral students.

6 Jul 2015

The trilingual magazine of the city of Barcelona, Barcelona Metropolis, dedicates its leading article and an extensive report to the biomedicine conducted in Barcelona.

Upcoming events

31 May - 02 Jun
ESADE Business School, Pedralbes Campus Avd. Esplugues 92-96, 08034 Barcelona
01 Jun
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Murielle Saade, IBMB-CSIC, Barcelona
02 Jun
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Dr. Roger Prades - Chief Scientific Officer, Iproteos S.L.