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Engineering genetic mutations in the mouse

28 Abr 22

The first session will concentrate on the well-established methods of classical transgenesis and gene-targeting via embryonic stem cells, and will include examples of how to produce a range of mutation types; for example over-expression models, gene knock-outs and point mutations, both constitutive and conditional.

The second session will address more recent developments, such as the use of gene-editing nucleases, their advantages and limitations, and novel methods of gene transfer.



Date: Thursday, 28 April 2022

Time: 09:30  – 13:00

Place: Tower D – Room 1 (Parc Científic de Barcelona)

Registration: Fill in the registration form here before 21 April. A confirmation email will be sent to all participants.  

The workshop is offered exclusively to members of IRB Barcelona and has limited places.
If you are registered to participate and finally cannot attend, please send an email to to give others the opportunity.


09:30 - 11:10 – 'Traditional' methods of transgenesis and gene targeting

11:10 – 11:30 –  BREAK
11:30 – 13:00 – Gene editing using sequence specific nucleases. Current and future trend


Stephen Forrow. Mouse Mutant Core facility Manager