Mitochondria sit at the core of immune cell decision-making. Beyond fuelling activation, they decide fate. Their shape, cristae architecture, membrane contacts, genome and core organelle functions generate signals that influence whether a T cell persists or exhausts, whether a macrophage inflames or resolves, and how tissues adapt to stress. By linking mitochondrial activities and molecular mechanisms to immune cell identity and function and tissue physiology, this meeting aims to build a more integrated view of mitochondria as active regulators of immunity.
Presentation
Following mitochondrial control from molecules to cells, tissues and the whole organism, we will move from signals generated within the organelle to the decisions that shape innate responses and adaptive fate and memory. We will then move beyond the immune cell, exploring how tissue niches, danger signals, ageing and organism-wide crosstalk reshape mitochondrial and immune states, and how these principles can ultimately be harnessed to rewire immunity in physiology and disease.
Bringing together researchers across mitochondrial biology, immunology, metabolism and medicine, we will trace how mitochondrial states become immune states, uncover shared principles across scales and define the questions that will shape the next generation of research at the interface of mitochondria and immunity.
Stefanie Wculek
IRB Barcelona
(Barcelona, Spain)
Ana Victoria Lechuga-Vieco
IRB Barcelona
(Barcelona, Spain)
Ping-Chih Ho
University of Lausanne and Ludwig Institute for Cancer Research at Lausanne branch
(Lausanne, Switzerland)
- €0 – Attendees affiliated with the organizing institution (IRB Barcelona)
- €121 Attendees from universities and other public institutions
- €242 Attendees from companies and industries from the private sector
Please note that we reserve the right to cancel your registration should your application not be accepted, in which case any fees paid will be fully refunded.
Priority will be given to those who submit the highest quality abstracts for short talks or posters and the order of registration will be considered.
Abstracts should include a title, authors, affiliations, summary (max 250 words) and references
REGISTRATION DEADLINE: 1 JULY, 2027
(Note: Any issue about the registration or abstract, please contact: meritxell.gavalda@irbbarcelona.org)
Programme
Monday, 8 November
8.30 Registration
9.00 Welcome by Directorate of IRB Barcelona and organisers (Stefanie Wculek, Ana Victoria Lechuga- Vieco and Ping-Chih Ho)
Session I: Signals from within - Mitochondrial Biology
Chair:
9.15 Title pending to confirm
Luca Scorrano, University of Padova (Padova, Italy)
9.45 Title pending to confirm
Julien Prudent, MRC Mitochondrial Biology Unit, University of Cambridge (Cambridge, UK)
10.15 Short talk 1
10.30 -11.30 Coffee break and poster session
Chair:
11.30 Mitochondrial signaling in adaptive immunity
Nav Chandel, Northwestern University Feinberg School of Medicine (Chicago, Illinois, USA)
12.00 Title pending to confirm
Ana Victoria Lechuga- Vieco (IRB Barcelona)
12.30 Short talk 2
12.45 Short talk 3
13.00 -14.45 Lunch and poster session
Session II: First responders – Innate Cell Biology
Chair:
14.45 Tissue Macrophage Metabolic Functions
Florent Ginhoux, Gustave Roussy (Villejuif, France)
15.15 Short talk 4
15.30 Short talk 5
15.45 – 16.30 Coffee break and poster session
Chair:
16.30 Title pending to confirm
Stefanie Wculek (IRB Barcelona)
17.00 Metabolic control of macrophage activation and inflammation
Jan van den Bossche, Amsterdam UMC (Amsterdam, The Netherlands)
17.15 Short talk 6
17.30 Short talk 7
18:00 End of session
Tuesday, 9 November
Session III: Fate and memory – Adaptive Cell Biology
Chair:
9.00 Braving the elements: Deciphering the role of mineral nutrients in T cell function
Erika Pearce, Johns Hopkins Bloomberg School of Public Health (Baltimore, MD, USA)
9.30 Metabolic control of T cell function
Mauro Corrado, CMMC/ University of Cologne (Cologne, Germany)
10.00 Short talk 8
10.15 -11.15 Coffee break and poster session
Chair:
11.15 S-Palmitoylation as a Metabolic Regulator of Mitochondrial Protein Function
Luciana Berod, Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg, University Mainz (Mainz, Germany)
11.45 Title pending to confirm
Sarah Pickett, Newcastle University, Medical School (Newcastle, UK)
12.15 Short talk 9
12.30 Short talk 10
12.45-14.30 Lunch and poster session
Session IV: Beyond the Cell – Tissue & Systemic
Chair:
14.30 Mitochondrial-Innate Immune Crosstalk in mtDNA Depletion Disorders
Phillip West, The Jackson Laboratory (Bar Harbor, ME, USA)
15.00 Title pending to confirm
David Sancho, CNIC (Madrid, Spain)
15.30 Short talk 11
15.45 – 16.30 Coffee break and poster session
Chair:
16.30 Title pending to confirm
Philipp Lang, Uniklinik Düsseldorf (Düsseldorf, Germany)
17.00 Title pending to confirm
Maria Mittelbrunn, Centro de Biología Molecular Severo Ochoa/ Universidad Autónoma de Madrid (Madrid, Spain)
17.30 Short talk 12
17.45 Short talk 13
18.00 End of session
20.30 Speakers and Short talk’s dinner
Wednesday, 10 November
Session V: Rewiring immunity – Therapy & Disease
Chair:
9.00 How immunometabolism is providing therapeutic targets for inflammatory diseases
Luke O’Neill, TCD School of Biochemistry and Immunology, Trinity College Dublin, The University of Dublin (Dublin, Ireland)
9.30 Title pending to confirm
Luis Ferreira Moita, Lisbon School of Medicine (Lisboa, Portugal)
9.45 Short talk 14
10.00 Short talk 15
10.30 -11.30 Coffee break and poster session
Chair:
11.30 Title pending to confirm
Katja Simon, Max Delbrück Center for Molecular Medicine (Berlin, Germany)
12.00 Title pending to confirm
Ping-Chih Ho (University of Lausanne and Ludwig Institute for Cancer Research at Lausanne branch)
12.30 Concluding remarks
12.45 End of conference
Venue
The BARCELONA BIOMED CONFERENCE Mitochondrial Control of Immune Cells will be placed at the Recinte Modernista de Sant Pau in Barcelona.
Recinte Modernista de Sant Pau
Sala Pau Gil (conference room)
Espai 1902 + Sala 1 pl. -1 (poster sessions + lunches & coffee breaks)
Accomodation
Speakers will be lodged at the Hotel Catalonia Sagrada Familia
Aragó, 577- 579
08026, Barcelona
Telephone: +34 93 245 89 05
Speakers
Poster
