Estefania Freire

Unit:

Structural & Computational Biology

Position:

Former - Lab Technician

Office:

EMPBC33

Email:

estefania.freire@irbbarcelona.org

Left IRB Barcelona in September 2014

Research Group

Molecular Modelling and Bioinformatics

Mecanismos de las Enfermedades

Selected group publications

Site-specific incorporation of a fluorescent nucleobase analog enhances i-motif stability and allows monitoring of i-motif folding inside cells

Mir, B; Serrano-Chacón, I; Medina, P; Macaluso, V; Terrazas, M; Gandioso, A; Garavís, M; Orozco, M; Escaja, N; González, C

Nucleic Acids Research,

(6 )

3375

- 3389

(2024)

Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway

González, L; Díaz, L; Pous, J; Baginski, B; Duran-Corbera, A; Scarpa, M; Brun-Heath, I; Igea, A; Martin-Malpartida, P; Ruiz, L; Pallara, C; Esguerra, M; Colizzi, F; Mayor-Ruiz, C; Biondi, RM; Soliva, R; Macias, MJ; Orozco, M; Nebreda, AR

Nature Communications,

(1 )

3318

(2023)

Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides

Genna, V; Iglesias-Fernández, J; Reyes-Fraile, L; Villegas, N; Guckian, K; Seth, P; Wan, B; Cabrero, C; Terrazas, M; Brun-Heath, I; González, C; Sciabola, S; Villalobos, A; Orozco, M

Nucleic Acids Research,

(10 )

4713

- 4725

(2023)

López-Güell, K; Battistini, F; Orozco, M

Nucleic Acids Research,

(6 )

2633

- 2640

(2023)

pH-Dependent Capping Interactions Induce Large-Scale Structural Transitions in i-Motifs