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Unraveling the complexity of cellular senescence

30 Jun 22

Speaker: Federico Pietrocola, PhD - GL - Department of Biosciences and Nutrition - Karolinska Institutet - Sweden

 
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Presentation

Speaker: Federico Pietrocola, PhD - GL - Department of Biosciences and Nutrition - Karolinska Institutet - Sweden

Date: Thursday, 30 June 2022 at 5PM

Place: Felix Serratosa Hall

Host:  Valentina Ramponi, PhD Student - Cellular Plasticity and Disease - Aging & Metabolism Programme

Abstract:

The role of senescent cells in aging and age-related pathologies is well established. Nonetheless, senescent cells exhibit remarkable - functional and molecular - heterogeneity, which limits the implementation of senescence-targeted therapies. In the lab, we are specifically interested in resolving the complexity of the senescent phenotype, aiming to shed light on the vulnerabilities that characterise pathologically meaningful senescent cells. Our current work focuses on identifying metabolic addictions of senescent cells, with particular emphasis on the role of arginine metabolism in the establishment and maintenance of the senescent state.  

 

Organizer: IRB Barcelona

IMPORTANT: For attendees outside the PCB community you must register at least 24h before the seminar.

 

 

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