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Investigación

A la vanguardia de la biomedicina

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Dra. Jessica Mainez

Mainez
Unit:
Position:
Lab Manager
Office:
EM01B22
Telephone:
+34 93 40 37026
Research Group

Selected group publications

A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
Nature
(2021)
Senolytic CAR T cells reverse senescence-associated pathologies.
Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW. (*equal contribution).
Nature
(2020)
An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants
Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.
Cancer Discovery
(2020)
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancer
Osmanbeyoglu HU, Shimizu F*, Rynne-Vidal A*, Alonso-Curbelo D*, Chen HA, Wen HY, Yeung TL, Jelinic P, Razavi P, Lowe SW, Mok SC, Chiosis G, Levine DA, Leslie CS. (*equal contribution).
Nature Communications
(2019)
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity
Finley LWS*, Vardhana SA*, Carey BW*, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, et al, [corr author] Thompson CB. (*equal contribution)
Nature Cell Biology
(2018)