IRB Barcelona logo

Recerca

A l'avantguarda de la biomedicina

Research header

Dra. Jessica Mainez

Jessica Mainez
Unit:
Position:
Lab Manager
Office:
EM01B22
Telephone:
+34 93 40 37026
Research Group

Selected group publications

Senescence rewires microenvironment sensing to facilitate anti-tumor immunity
Chen HA; Ho YJ; Mezzadra R; Adrover JM; Smolkin R; Zhu C; Woess K; Bernstein N; Schmitt G; Fong L; Luan W; Wuest A; Tian S; Li X; Broderick C; Hendrickson RC; Egeblad M; Chen Z; Alonso-Curbelo D; Lowe SW
Cancer Discovery
CD -
0528
(2022)
Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas
Cassandra Burdziak †, Direna Alonso-Curbelo †, Thomas Walle, Francisco M. Barriga, José Reyes, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Daniela Quail, Richard Koche, Linas Mazutis, Tal Nawy, Ronan Chaligné, Scott W. Lowe, Dana Pe'er. († equal contribution)
bioRxiv
(2022)
A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
Nature
(2021)
Senolytic CAR T cells reverse senescence-associated pathologies.
Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW. (*equal contribution).
Nature
(2020)
An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants
Paz Zafra M, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Calvo Fernandez MT, Wilkinson JE, Piskounova E and Dow LE.
Cancer Discovery
(2020)