Skip to main content
Google Tag Manager
EN
CAT
CAST
Toggle navigation
×
Donar
Menu Search
El IRB
Noticias
Eventos
Alumni & Community
Menú principal
Investigación
Jóvenes Científicos
Transferencia tecnológica
Divulgación
Main Menu Mobile
Investigación
Jóvenes Científicos
Transferencia tecnológica
Divulgación
Alumni & Comunidad
Noticias
Eventos
El IRB
Patrick Aloy
Research Group:
Structural Bioinformatics and Network Biology
Unit:
MECHANISMS OF DISEASE
Position:
Group Leader
Office:
CL01C72-73
Telephone:
+34 93 40 39690
Email:
paloy@irbbarcelona.org
ICREA Research Professor, ERC Consolidator Grant
View research group
Meet our scientists Videos
Patrick Aloy: "Redes de vida"
Selected group publications
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns
Lidia Mateo , Miquel Duran-Frigola , Albert Gris-Oliver , Marta Palafox , Maurizio Scaltriti , Pedram Razavi , Sarat Chandarlapaty , Joaquin Arribas , Meritxell Bellet , Violeta Serra , Patrick Aloy
Genome Med,
12
(1), 78 (2020)
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker
Miquel Duran-Frigola, Eduardo Pauls, Oriol Guitart-Pla, Martino Bertoni, Víctor Alcalde, David Amat, Teresa Juan-Blanco, Patrick Aloy
Nat Biotechnol,
38
(9), 1087 (2020)
Formatting biological big data for modern machine learning in drug discovery
Duran-Frigola M., Fernandez-Torras A., Bertoni M., Aloy P.
Wiley Interdiscip Rev Comput Mol,
9
(6), (2019)
Formatting biological big data for modern machine learning in drug discovery
Duran-Frigola M., Fernández-Torras A., Bertoni M., Aloy P.
Wiley Interdiscip. Rev. Comput. Mol.,
(2018)
Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer
Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR and Aloy P.
Cancer Res,
77
(2), 459-469 (2017)
Residues Coevolution Guides the Systematic Identification of Alternative Functional Conformations in Proteins
Sfriso P, Duran-Frigola M, Mosca R, Emperador A, Aloy P and Orozco M.
Structure,
24
(1), 116-26 (2016)
A chemo-centric view of human health and disease
Duran-Frigola M, Rossell D and Aloy P.
Nat Commun,
5
5676 (2014)
Interactome3D: adding structural details to protein networks
Mosca R, Céol A and Aloy P.
Nat Methods,
10
(1), 47-53 (2013)
Structural systems pharmacology: the role of 3D structures in next-generation drug development
Duran-Frigola M, Mosca R and Aloy P.
Chem Biol,
20
(5), 674-84 (2013)
The role of structural disorder in the rewiring of protein interactions through evolution
Mosca R, Pache RA and Aloy P.
Mol Cell Proteomics,
11
(7), M111.01496 (2012)
Interactome mapping suggests new mechanistic details underlying Alzheimer's disease
Soler-López M, Zanzoni A, Lluís R, Stelzl U and Aloy P.
Genome Res,
21
(3), 364-76 (2011)
Novel peptide-mediated interactions derived from high-resolution 3-dimensional structures
Stein A and Aloy P.
Plos Comput Biol,
6
(5), e1000789 (2010)
Uncovering new substrates for Aurora A kinase
Sardon T, Pache RA, Stein A, Molina H, Vernos I and Aloy P.
Embo Rep,
11
(12), 977-84 (2010)
Patronos:
Centro:
Miembro de:
Reconocidos por: