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Studying cell fate transitions in mammalian epidermis

23 nov. 18

Speaker: Fiona M. Watt FRS FMedSci. Director, Centre for Stem Cells and Regenerative Medicine, King's College London. London. UK



Organizers: IRB Barcelona
Date: Friday 23 November, 12.00h
Place: Auditorium, Parc Científic de Barcelona, Spain

Host: Dr. Salvador Aznar Benitah (IRB Barcelona)   


Our current knowledge of tissue-resident stem cells is based largely on end-point analysis of cell populations. However, to understand tissue dynamics it is essential to analyse changes in the state of individual cells that occur within minutes or hours. In my presentation I will describe how by integrating data from live cell imaging and single cell RNAseq we are starting to understand epidermal cell state transitions and the mechanisms that control them. Insights into the nature of these transitions can provide new information about epidermal inflammation and cancer.

Plenary Seminar