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Recerca

A l'avantguarda de la biomedicina

David Fernández

Unit:
Position:
Technical Officer
Office:
EMS1C14BIS
Telephone:
+34 93 40 39803
Research Group

Selected group publications

Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemic driver mutations
Singh, I; Fernandez-Perez, D; Sanchez, PS; Rodriguez-Fraticelli, AE
Cell Stem Cell,
32
(4 )
564
- 580
(2025-04-03)
A single-cell resolved genotype-phenotype map using genome-wide genetic and environmental perturbations
Nadal-Ribelles, M; Solé, C; Díez-Villanueva, A; Attolini, CSO; Matas, Y; Steinmetz, L; de Nadal, E; Posas, F
Nature Communications,
16
(1 )
2645
(2025-03-18)
H4K20me3-Mediated Repression of Inflammatory Genes Is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
Ramponi, V; Richart, L; Kovatcheva, M; Attolini, CSO; Capellades, J; Lord, AE; Yanes, O; Ficz, G; Serrano, M
Cancer Research,
85
(1 )
32
- 51
(2025-01-02)
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells
López-Polo, V; Maus, M; Zacharioudakis, E; Lafarga, M; Attolini, CSO; Marques, FDM; Kovatcheva, M; Gavathiotis, E; Serrano, M
Nature Communications,
15
(1 )
7378
(2024-08-27)
Human EWS-FLI protein levels and neomorphic functions show a complex, function-specific dose-response relationship in Drosophila.
Mahnoor S; Molnar C; Velázquez D; Reina J; Llamazares S; Heinen JP; Mora J; Gonzalez C
Open Biology,
14
(7 )
240043
(2024-07-01)
TrxT and dhd are dispensable for Drosophila brain development but essential for l(3)mbt brain tumour growth
Molnar, Cristina; Heinen, Jan Peter; Reina, Jose; Llamazares, Salud; Palumbo, Emilio; Pollarolo, Giulia; Gonzalez, Cayetano
Embo Reports,
25
(7 )
2842
- 2860
(2024-05-15)
Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms
Anna Oncins, Roser Zaurin, Houyem Toukabri, Kimberly Quililan, José R Hernández Mora, Magdalena A Karpinska, Erik Wernersson, Alastair Smith, Agostina Bianchi, Leone Albinati, Andrea Rivero, François Serra, Raúl Gómez, Cristina López, Sílvia Beà, Nadia Halidi, Alfonso Valencia, Magda Bienko, A Marieke Oudelaar, Renée Beekman.
bioRxiv 2024.10.07.616925,
(2024)
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype
Maus, M; López-Polo, V; Mateo, L; Lafarga, M; Aguilera, M; De Lama, E; Meyer, K; Sola, A; Lopez-Martinez, C; López-Alonso, I; Guasch-Piqueras, M; Hernandez-Gonzalez, F; Chaib, S; Rovira, M; Sanchez, M; Faner, R; Agusti, A; Diéguez-Hurtado, R; Ortega, S; Manonelles, A; Engelhardt, S; Monteiro, F; Attolini, CSO; Prats, N; Albaiceta, G; Cruzado,...
Nature Metabolism,
(5 )
2111
- 2130
(2023-12-14)
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair
Kovatcheva, M; Melendez, E; Chondronasiou, D; Pietrocola, F; Bernad, R; Caballe, A; Junza, A; Capellades, J; Holguín-Horcajo, A; Prats, N; Durand, S; Rovira, M; Yanes, O; Attolini, CSO; Kroemer, G; Serrano, M
Nature Metabolism,
5
(11 )
1911
- 1930
(2023-11-16)