Jordina Guillén

Position:

Alumni - Postdoctoral Fellow

Office:

EMPBB52-53

Telephone:

+34 93 40 31901

Email:

jordina.guillen@irbbarcelona.org

Left IRB Barcelona in November 2016

Research Group

Translational Control of Cell Cycle and Differentiation

Mecanismes de Malaltia

Selected group publications

Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD

Garcia-Cabau C; Bartomeu A; Tesei G; Cheung KC; Pose-Utrilla J; Picó S; Balaceanu A; Duran-Arqué B; Fernández-Alfara M; Martín J; De Pace C; Ruiz-Pérez L; García J; Battaglia G; Lucas JJ; Hervás R; Lindorff-Larsen K; Méndez R; Salvatella X

NATURE,

637

(8045 )

496

- 503

(2025)

Antitumor T‐cell function requires CPEB4‐mediated adaptation to chronic endoplasmic reticulum stress

Fernández-Alfara, M; Sibilio, A; Martin, J; Uxó, ET; Malumbres, M; Alcalde, V; Chanes, V; Cañellas-Socias, A; Palomo-Ponce, S; Batlle, E; Méndez, R

Embo Journal,

(9 )

e111494

(2023)

Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

Duran-Arqué, B; Cañete, M; Castellazzi, CL; Bartomeu, A; Ferrer-Caelles, A; Reina, O; Caballé, A; Gay, M; Arauz-Garofalo, G; Belloc, E; Mendez, R

Genome Biology,

(1 )

192

(2022)

Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation

Suñer, C; Sibilio, A; Martín, J; Castellazzi, CL; Reina, O; Dotu, I; Caballé, A; Rivas, E; Calderone, V; Díez, J; Nebreda, AR; Méndez, R

Elife,

e75873

(2022)

The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer

Pascual, R; Martín, J; Salvador, F; Reina, O; Chanes, V; Millanes-Romero, A; Suñer, C; Fernández-Miranda, G; Bartomeu, A; Huang, YS; Gomis, RR; Méndez, R

Science Advances,

(20 )

eaax3868

(2020)

Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing

Parras, A; Anta, H; Santos-Galindo, M; Swarup, V; Elorza, A; Nieto-González, JL; Picó, S; Hernández, IH; Díaz-Hernández, JI; Belloc, E; Rodolosse, A; Parikshak, NN; Peñagarikano, O; Fernández-Chacón, R; Irimia, M; Navarro, P; Geschwind, DH; Méndez, R; Lucas, JJ

Nature,

560

(7719 )

441

(2018)

Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs

Weill, L; Belloc, E; Castellazzi, CL; Méndez, R

Nature Structural & Molecular Biology,

(8 )

672

(2017)

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress