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Recerca

A l'avantguarda de la biomedicina

Research header

Sophia Ivaschuk

IRB Barcelona
Unit:
Position:
Visiting Student
Office:
EM01B24
Telephone:
+34 93 40 37123
Research Group

Selected group publications

Identification and selectivity profiling of small-molecule degraders via multi-omics approaches.
Scholes, N. S., Mayor-Ruiz, C. & Winter, G. E.
Cell Chemical Biology
(2021)
Rational discovery of molecular glue degraders via scalable chemical profiling
Mayor-Ruiz, C., Bauer, S., Brand, M., Kozicka, Z., Siklos, M., Imrichova, H., Kaltheuner, I., Hahn, E., Seiler, K., Koren, A., Petzold, G., Fellner, M., Bock, C., Mueller, A.C., Zuber, J., Geyer, M., Thomä, N.H., Kubicek, S., Winter, G.E
Nat Chem Bio
(2020)
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
Mayor-Ruiz, C.1,*, Jaeger, M.G*, Bauer, S., Brand, M., Sin, C., Hanzl, A., Mueller, A.C., Menche, J., and Winter, G.E.1
1 co-corresponding; *Co-first authors
Molecular Cell
(75 )
849 -
858
(2019)
Identification and characterization of cancer vulnerabilities via targeted protein degradation
Mayor-Ruiz, C., and Winter, G.E
Drug Discov Today Technol
(31 )
81 -
90
(2019)
ERF deletion rescues RAS deficiency in mouse ES cells
Mayor-Ruiz C., Olbrich T., Drosten M., Lecona E., Vega-Sendino M., Ortega S., Dominguez O., Barbacid M., Ruiz S. & Fernandez-Capetillo O
Genes & Dev
(32 )
568 -
576
(2018)