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A l'avantguarda de la biomedicina

Craig Donoghue

Unit:
Position:
Alumni - Postdoctoral Fellow
Office:
EM01B11-12
Telephone:
+34 93 40 37096
Left IRB Barcelona in December 2019
Research Group

Selected group publications

Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation
Cabré, A; Verdaguer, X; Riera, A
Chemical Reviews,
122
(1 )
269
- 339
(2022)
Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease
Rol, A; Todorovski, T; Martin-Malpartida, P; Escolà, A; Gonzalez-Rey, E; Aragón, E; Verdaguer, X; Vallès-Miret, M; Farrera-Sinfreu, J; Puig, E; Fernández-Carneado, J; Ponsati, B; Delgado, M; Riera, A; Macias, MJ
Nature Communications,
12
(1 )
1869
(2021)
Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation
Donoghue, C; Cubillos-Rojas, M; Gutierrez-Prat, N; Sanchez-Zarzalejo, C; Verdaguer, X; Riera, A; Nebreda, AR
European Journal Of Medicinal Chemistry,
201
112451
(2020)
Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions
Ros, E; Bellido, M; Verdaguer, X; de Pouplana, LR; Riera, A
Bioconjugate Chemistry,
31
(3 )
933
- 938
(2020)
P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis
Cabré, A; Riera, A; Verdaguer, X
Accounts Of Chemical Research,
53
(3 )
676
- 689
(2020)
Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols
Cabre, A; Rafael, S; Sciortino, G; Ujaque, G; Verdaguer, X; Lledos, A; Riera, A
Angewandte Chemie (International Ed. Print),
59
(19 )
7521
- 7527
(2020)
Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides
Cabré, A; Romagnoli, E; Martínez-Balart, P; Verdaguer, X; Riera, A
Organic Letters,
21
(23 )
9709
- 9713
(2019)
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
Salomó, E; Gallen, A; Sciortino, G; Ujaque, G; Grabulosa, A; Lledós, A; Riera, A; Verdaguer, X
Journal Of The American Chemical Society,
140
(49 )
16967
- 16970
(2018)
Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines
Cabré, A; Sciortino, G; Ujaque, G; Verdaguer, X; Lledós, A; Riera, A
Organic Letters,
20
(18 )
5747
- 5751
(2018)