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Research

At the forefront of biomedicine

Dr. Denise Duma

IRB Barcelona
Unit:
Position:
Former -
Postdoctoral Fellow
Office:
EM01B22
Telephone:
+34 93 40 37026
Left IRB Barcelona in May 2023
Research Group

Selected group publications

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data
Burdziak C, Zhao CJ, Haviv D, Alonso-Curbelo D, Lowe SW, Pe'er D
Bioinformatics
39
(39 Suppl 1 )
i394 -
i403
(2023)
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis
Burdziak C*, Alonso-Curbelo D*, Walle T, Reyes J, Barriga FM, Haviv D, Xie Y, Zhao Z, Zhao CJ, Chen HA, Chaudhary O, Masilionis I, Choo ZN, Gao V, Luan W, Wuest A, Ho YJ, Wei Y, Quail DF, Koche R, Mazutis L, Chaligné R, Nawy T, Lowe SW, Pe'er D
(*) these authors contributed equally
Science
380
(6645 )
eadd5327 -
eadd5327
(2023)
Senescence rewires microenvironment sensing to facilitate anti-tumor immunity
Chen HA, Ho YJ, Mezzadra R, Adrover JM, Smolkin R, Zhu C, Woess K, Bernstein N, Schmitt G, Fong L, Luan W, Wuest A, Tian S, Li X, Broderick C, Hendrickson RC, Egeblad M, Chen Z, Alonso-Curbelo D, Lowe SW
Cancer Discovery
13
(2 )
432 -
453
(2023)
A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
Nature
(2021)
Senolytic CAR T cells reverse senescence-associated pathologies
Amor C*, Feucht J*, Leibold J*, Ho Y-J, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, et al, Sadelain M, Lowe SW.
(*) these authors contributed equally
Nature
(2020)