Obesity is a world health problem since excessive accumulation of fat tissue (or adipose tissue) increases the risk of cardiovascular disease, hypertension, diabetes and some types of cancer.
DOR protein deficiency favours the development of obesity
Marta Vilaseca: "The information provided by mass spectrometry facilitates the understanding of diseases"
Researchers demonstrate the presence of stable beta-amyloid dimers in the brains of patients with Alzheimer’s disease
LAT2 and TAT1 transporters collaborate in the renal reabsorption of neutral amino acids
Marta Vilaseca (Barcelona, 1970) leads the Mass Spectrometry & Proteomics Co
The most widely used biomarkers for the early detection of Alzheimer’s disease (AD) are currently the concentrations of beta-amyloid and phosphorylated Tau in cerebrospinal fluid.
A scientific team has described for the first time the in vivo synergy action of the neutral amino acid transporters LAT2 and TAT1 and their participation in the renal absorption.
La Vanguardia newspaper has published an article about the eight Catalan projects that have been awarded a grant from the European Research Council. The research of Salvador Aznar Benitah from IRB Barcelona is among these projects.
Gen magazine, Phys Org, News Medical Life Sciences, among other international media, have published an article on the latest study led by Antonio Zorzano from IRB Barcelona, which supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation.
La Vanguardia has published an article about the "Vanguardia de la Ciencia" award ceremony. The winners of these awards were selected by readers, who vote among eight Spanish researchers in the field of physics, chemistry, biology and social sciences.
Felice Alessio Bava
IRB Barcelona Alumni member
«We suspected that CPEB1, a protein involved in regulating mRNA translation in the cytoplasm, might also be active in the nucleus and play a role in controlling pre-mRNA processing. We discovered that it affects the alternative generation in the mature mRNA of the 3'-UTR, regions where most of the elements regulating translation in time and space are located.»
More info about this news here.
«Controlling a biological process from outside is the future of chemistry and opens up promising roads for advancements in pharmacological research.»
More info on this news here.
«98% of the potential therapeutic molecules against diseases of the central nervous system cannot cross the blood-brain barrier. We develop peptides with the capacity to open the doors of the barrier and act as shuttles when attached to a therapeutic molecule.»
«Our study highlights the complexity of p38 functions, both in cancer and in the maintenance of normal tissues. It shows why an inhibitor of this molecule could effectively have undesirable side effects. But these do not exclude it from being a target against cancer.»
More on this news here.
Datos básicos sobre IRB
IRB Barcelona has been awarded the "HR Excellence in Research" logo. This recognition reflects the commitment of the Institute to continuously improving its human resources policies in line with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers. The award confirms the efforts of the Institute to ensure fair and transparent recruitment and appraisal procedures. Click here for more information.
IRB Barcelona is home to nearly 450 research, technical and support staff from 35 countries who share the common goal of contributing to the advancement of the biomedical sciences through investigator–driven research, and improving quality of life by applying advances in this field.
The convergence of biology, chemistry, and structural and computational biology is unique at IRB Barcelona and opens a strategic window to gain insight into basic molecular processes in health and disease.
Research is conducted by 23 groups organized into 5 interdisciplinary programmes. Each programme includes a diverse faculty of researchers with overlapping scientific interests. The research areas have been structured to be highly interactive, fostering multidisciplinarity by combining modern molecular biology, classical genetics, biochemistry, structural biology, bioinformatics, systems biology, advanced microscopy, and genomic and proteomic approaches.