<p>To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin for degradation. Francisco Martínez, IRB Barcelona.</p>
    Scientific news
    Researchers at IRB Barcelona study how altered protein degradation contributes to the development of tumours
    Nature Cancer
    <p>Researchers at IRB Barcelona have identified these genetic footprints produced by some cancer treatments and have for the first time been able to calculate the genetic toxicity of some of these treatments. Claudia Arnedo, IRB Barcelona.</p>
    Scientific news
    Genetic alterations caused by cancer therapies identified
    Nature Genetics
    <p>The SMAD2 protein can have two orientations. Green indicates the open configuration that allows DNA binding and red the closed configuration, which is incompatible with such binding. Maria J. Macias, IRB Barcelona.</p>
    Scientific news
    Scientists decipher the keys underlying the differences between SMAD2 and SMAD3, two almost identical transcription factors but with distinct roles
    Genes & Development

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    19 Dec
    Notch blockade induces dramatic metabolic changes that may reflect a switch of thyroid cell fate or function
    Fèlix Serratosa, Parc Cientific de Barcelona
    Speaker:
    Lluc Mosteiro, Ph.D., Chris Siebel’s lab - Genentech - San Francisco, CA - USA
    21 Jan
    Mechanisms regulating tumor transition states
    Felix Serratosa Hall, Parc Cientific de Barcelona
    Speaker:
    Cédric Blanpain, Ph.D. WELBIO. Laboratory of Stem Cells and Cancer. Université Libre de Bruxelles (ULB). Brussels. Belgium
    31 Jan
    Charting genome maintenance and synthetic lethality networks
    Auditorium, Parc Cientific de Barcelona
    Speaker:
    Daniel Durocher, PhD, The Lunenfeld-Tanenbaum Research Institute. Mount Sinai Hospital. Toronto. Canada

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