Results about: disease

The group directed by Prof. Guinovart is involved in several projects on glycogen metabolism and its dysfunctions in diabetes and Lafora disease.

DOR protein deficiency favours the development of obesity

Researchers at IRB Barcelona discover the mechanism that leads to a less harmful form of obesity that is associated with the number rather than volume of fat cells.

There are several types of obesity and some are more harmful than others.

The study has been published in the journal Nature Cell Biology.

A tool developed at IRB Barcelona to be used by the international consortium Pan-Cancer for the analysis of human tumours

dSysMap (which stands for “Disease-mutations Systemic Mapping”) is a computational tool to interpret the effect of genetic mutations on the development of complex diseases.

The tool allows researchers to explore how alterations in more than 2,000 proteins affect the diverse biological functions in which these molecules are involved.

The Pan-Cancer consortium has included the tool in order to gain a more global view of the causes of tumour development.