

Joan J.Guinovart
IRB Barcelona Director (2005 - 2018)
2017: a spectacular year of achievements
In 2017, IRB Barcelona made some great achievements, bringing about significant scientific results and important institutional accomplishments.
As an example of one such accomplishment, at the end of the year, we were named for the first time beneficiary of a bequest, amounting to 1.5M €, made by a couple from Barcelona. In line with their wishes, this bequest will be used to fund projects on cancer and metastasis. Proud of this achievement and grateful for the trust placed in us, we will endeavour to make the best use of this donation.
Only by excelling in science, our raison d’être, can we rise to meet the expectations of society. In 2017, we continued to strengthen our position, and indeed achieved a great impact in the scientific community, with 188 scientific papers published, 93.1% of our articles falling in the first quartile and 77.7% in the first decile of scientific journals with the highest impact.
These outstanding achievements came about from the labour of our exceptional community, formed by talented professionals—who we strive to attract. Last year the scientific capacity of IRB Barcelona was boosted through the joining of Fran Supek, an outstanding young group leader, and Manuel Serrano, an internationally recognised scientist. Backed by ERC funding, they have chosen to pursue their careers in the stimulating and competitive environment provided by our Institute.
As a public research centre, IRB Barcelona is subjected to periodic appraisals by our Trustees and Evaluation Committees. In 2017, we achieved a maximum score in an evaluation conducted by the CERCA Institution. In this regard, the report stated that IRB Barcelona is performing science at an international level and that it has shown outstanding development in recent years.
Furthermore, in 2017, we continued to channel efforts into increasing our international presence through flagship European projects, maintaining our leadership in science and innovation, strengthening our position by fostering synergies with the other BIST centres, consolidating our Alumni network, and further exploring ways to build on our relationship with the public. Our wide and rich community kept on tackling challenges, overcoming obstacles and developing cutting-edge research of excellence, thus allowing IRB Barcelona to flourish.
Visit our Scientific Discoveries and Institutional Highlights to learn more about IRB Barcelona’s achievements in 2017.
2017: a spectacular year of achievements
IRB Barcelona made some great achievements, bringing about significant scientific results and important institutional accomplishments.
Joan J.Guinovart
IRB Barcelona Director (2005 - 2018)

Discoveries


Selected publications
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Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress
Solanas G, et al. Cell. 2017 Aug 10; 170(4):678-692.e20.
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Reduced mutation rate in exons due to differential mismatch repair
Frigola J, et al. Nat Genet. 2017 Dec; 49(12):1684-1692.
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Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells
Barriga FM, et al. Cell Stem Cell. 2017 Jun 1; 20(6):801-816.e7.
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Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress
Maillo C, et al. Nat Cell Biol. 2017 Feb; 19(2):94-105.
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Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment
Testoni G, et al. Cell Metab. 2017 Jul 5; 26(1):256-266.e4.
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Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control
Ramírez S, et al. Cell Metab. 2017 Jun 6; 25(6):1390-1399.e6.
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Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs
Weill L, et al. Nat Struct Mol Biol. 2017 Aug; 24(8):672-681.
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Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin
Bayona-Feliu A, et al. Nat Commun. 2017 Aug 18; 8(1):283.
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JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling
Recasens-Alvarez C, et al. Nat Commun. 2017 Jan 3; 8:13815.
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Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors
Martin-Malpartida P, et al. Nat Commun. 2017 Dec 12; 8(1):2070.
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Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators
De Mol E, et al. Structure. 2018 Jan 2; 26(1):145-152.e3.
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Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies
Villanueva E, et al. Nat Commun. 2017 Mar 16; 8:14833.
- Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging Sebastián D, et al. Trends Mol Med. 2017 Mar; 23(3):201-215.
- A PanorOmic view of personal cancer genomes Mateo L, et al. Nucleic Acids Res. 2017 Jul 3; 45(W1):W195-W200
- How accurate are accurate force-fields for B-DNA? Dans PD, et al. Nucleic Acids Res. 2017 Apr 20; 45(7):4217-4230.
Institutional highlights
Facts & Figures
Publications

Publications

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Q1 Publications
SJR 2016

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D1 Publications
SJR 2016
TRENDS IN Q1/D1 SINCE 2013
