Presentation
Organizer: IRB BioMed Seminars
Date / Time: Friday, July 10th at 12:00
Place: Auditorium Room
Speaker: Marcos Malumbres, Ph.D. - Group Leader of the Cancer Cell Cycle Group at the Vall d'Hebron Institute of Oncology (VHIO) in Barcelona. https://malumbreslab.org/
Host: Marco Milán, Ph.D. - Programme Chair - Group Leader, IRB Barcelona - Mechanisms of Disease Programme
Summary:
Cyclins and cyclin-dependent kinases shape cancer biology beyond their canonical roles in cell-cycle control. By integrating molecular, cellular, and translational approaches, we aim to understand how deregulated CDK networks contribute to tumor initiation, progression, and therapeutic resistance. In particular, we are interested in cell-type and tumor-type specific functions, as well as cellular mechanisms that contribute to plasticity and evolution in tumor cells and in response to treatments. By moving from individual cell-cycle components toward an integrated view of cyclin-CDK regulatory networks, our research aims to identify vulnerabilities that may improve patient stratification, overcome resistance, and guide the development of more effective therapeutic strategies in cancer.

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