The project presented by Ernest Giralt (IRB Barcelona) and Jordi Vila (ISGLOBAL) has been awarded € 260,000.
Of the 214 projects that applied for funding, 36 were selected on the basis of the evaluation of 103 scientists.
This is the third time that the IRB Barcelona researcher has received funding from “La Marató”.
The team headed by Núria López-Bigas has published an article in Cell about what might have favoured the periodicity of certain base pairs in the genomes of eukaryotic organisms.
The structure adopted by DNA when packaged inside cells influences the periodicity observed.
On Monday 22 October, the Dolors Aleu Hall registered a full house, with more than 170 people gathering to celebrate the long and successful career of Joan J. Guinovart. Authorities, current and former members of the Board of Trustees, scientific collaborators, family members, representatives from philanthropic institutions, members of IRB Barcelona, and former students accompanied the founder and former director of the institute during 13 years on this special occasion. Indeed, due to interest in the event, it was retransmitted by video streaming in an annex hall. In total, more than 200 people rendered tribute to a life dedicated to biochemistry and science outreach.
A study done at IRB Barcelona and the Vrije Universiteit Brussel identifies camelid nanobodies able to block EGF, a protein that is abundant in tumour cells and that helps them to proliferate.
Most solid tumours with metastatic potential show a high degree of chromosomal instability.
A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour.
The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour.
The projects address breast, lung, colon, prostate and melanoma cancer.
25 non-profit organisations working in the fields of social welfare, the environment, and biomedical research and associated with the LegadoSolidario.org campaign inform the public about the possibility of including a donation to a cause or charity with which they identify.
According to data from 2015, only 1% of wills made in Spain included a charitable bequest.
IRB Barcelona has been awarded two ERC PoC grants to optimise and validate tools with potential clinical applications.
Angel R. Nebreda’s project seeks to develop treatments to reduce the cardiotoxicity caused by chemotherapy.
Eduard Batlle’s project will build a biobank of mouse tumour organoids with the aim to contribute to the treatment of patients with advanced colon cancer.
A project headed by Antonio Zorzano at IRB Barcelona has been awarded funding from the BBVA Foundation to explore a possible link between ageing and cancer.
Called MitoFuss, the project focuses on the mitochondrial protein Mitofusin 2.
Manuel Serrano, ICREA researcher at IRB Barcelona, is the subject of the next video in the Meet Our Scientists series: “Killing zombie cells”.
In the video, Serrano talks about the work undertaken in his lab to find compounds that can remove damaged cells from the body.