The European Research Council (ERC) has awarded three ERC Advanced Grants to the Institute for Research in Biomedicine (IRB Barcelona), which account for 20% of the 15 grants awarded to centres in Spain, according to information provided by the European research organisation. Likewise, the ERC statistics for the 2011 call reveal that of the 2284 projects presented, 294 passed the screening process, which represents a success rate of 13%. Advanced Grants are the most competitive in Europe both in terms of funding and in terms of the reduced number of consolidated European researchers able to achieve one....
For several decades the pharmaceutical industry has been interested in achieving peptide analogues —similar molecules with improved properties— of the natural hormone somatostatin. This hormone and another two analogue compounds, octreotide and lanreotide, are used for the treatment of several kinds of neoplasia, such cancer of the thyroid, pancreas and prostate, in diseases associated with the growth hormone, for example in gigantism, and in digestive hemorrhages. Headed by...
A collaborative project run by the Institute for Research in Biomedicine (IRB Barcelona) and Vall d’Hebron Institute of Oncology (VHIO) has received one of the funding concessions of the first call of the “Prova’t” programme, promoted by the “Generalitat de Catalunya” (Autonomous Government of Catalonia). “Prova’t” seeks to boost the transfer of results from research centres in Catalonia to the productive sector.
The project will develop a new therapeutic strategy for glioblastoma, a very aggressive type of brain cancer with poor prognosis. This research involves the work of scientists Meritxell Teixidó and Ernest Giralt, at IRB Barcelona, and Joan Seoane at VHIO.
• This transformation, which is common in embryonic development, is
very similar to the process undergone by metastatic tumour cells.
• The gene GATA 6 is sufficient and necessary for this change
to happen. This gene is associated with many tumours of endodermal
origin, such as those of the liver, pancreas and colon.
The research, published in the journal Nature Genetics,
has addressed the genome of 100 patients with leukaemia and identified
that more than 1000 genes are mutated in the development of this
This study is a significant step forward to achievement of the
objectives set out by the Spanish Chronic Lymphocytic Leukaemia Genome
• The study focuses on the protein Ler, which is present in the pathogenic strains of Escherichia coli that caused an outbreak of food poisoning in Germany last May.
• Ler binds multiple DNA sequences, thereby activating numerous genes responsible for bacterial virulence.
• The findings of the study have been published in PloS Pathogens.
Nature Medicine publishes a pioneering study about a protein that regulates the expression of hundreds of genes that have a crucial role in the progression of pancreatic cancer, gliomas and possibly many other kinds of tumor.
Today the Minister of Science and Innovation, Cristina Garmendia, has presented the distinctions to the directors of the awarded centres.
The Ministry of Science and Innovation gives an INNCIDE award to the centre’s strategic technology transfer project.
This initiative is a practical course on cell biology that aims to improve science teaching in secondary schools.