News

Scientific news
<p>Skin of a young mouse. The image shows a cross section of the skin with the fibroblasts indicated in green. The thickness of the dermis and the density of fibroblasts is much greater in young skin than in aged skin– cell nuclei, in blue (M Salzer, IRB Bar</p>
8 Nov 2018

A study in mice done at IRB Barcelona and CNAG-CRG explains that dermal fibroblasts lose their cell identify over time and with it their capacity to produce and secrete collagen and other proteins.

Institutional news
<p>Roger Gomis, head of the Growth Control and Cancer Metastasis Lab</p>
2 Nov 2018

The Spanish Association of Cancer Research recognizes his work and grants him the ASEICA Young Investigator Award 2018.

The award ceremony will be held in Valencia on 6, 7 and 8 November.

Institutional news
<p>Ernest Giralt receives the diploma at La Marató ceremony</p>
2 Nov 2018

The project presented by Ernest Giralt (IRB Barcelona) and Jordi Vila (ISGLOBAL) has been awarded € 260,000.

Of the 214 projects that applied for funding, 36 were selected on the basis of the evaluation of 103 scientists.

This is the third time that the IRB Barcelona researcher has received funding from “La Marató”.

Scientific news
<p>The DNA molecule, formed by a double helix, winds around histone molecules twice, thus forming nucleosomes. The pink regions indicate those enriched in Adenine/Thymine base pairs (Author: Iris Joval Granollers)</p>
1 Nov 2018

The team headed by Núria López-Bigas has published an article in Cell about what might have favoured the periodicity of certain base pairs in the genomes of eukaryotic organisms.

The structure adopted by DNA when packaged inside cells influences the periodicity observed.

Institutional news
25 Oct 2018

On Monday 22 October, the Dolors Aleu Hall registered a full house,  with more than 170 people gathering to celebrate the long and successful career of Joan J. Guinovart. Authorities, current and former members of the Board of Trustees, scientific collaborators, family members, representatives from philanthropic institutions, members of IRB Barcelona, and former students accompanied the founder and former director of the institute during 13 years on this special occasion. Indeed, due to interest in the event, it was retransmitted by video streaming in an annex hall. In total, more than 200 people rendered tribute to a life dedicated to biochemistry and science outreach.

At 18:00...

Scientific news
<p>Figure showing the binding of a nanobody derived from alpaca to the EGF protein. The scientists demonstrate the high affinity and selectivity of a family of nanobodies for EGF, target of interest for the treatment of cancer (S Guardiola, IRB Barcelona)</p>
2 Oct 2018

A study done at IRB Barcelona and the Vrije Universiteit Brussel identifies camelid nanobodies able to block EGF, a protein that is abundant in tumour cells and that helps them to proliferate.

Scientific news
<p>Drosophila epithelium subjected to chromosomal instability (CIN): cells start invading the neighbouring tissues. Magenta labels the nuclei of all the epithelium while green labels the membranes of cells subjected to CIN (L Barrio, IRB Barcelona)</p>
26 Sep 2018

Most solid tumours with metastatic potential show a high degree of chromosomal instability.

A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour.

The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour.

Institutional news
<p>The AECC ceremony was held in Madrid yesterday, 25th September, the World Cancer Research Day</p>
25 Sep 2018

The projects address breast, lung, colon, prostate and melanoma cancer.

Institutional news
<p>"Legado Solidario" Campaign. Source: Legadosolidario.org</p>
13 Sep 2018

25 non-profit organisations working in the fields of social welfare, the environment, and biomedical research and associated with the LegadoSolidario.org campaign inform the public about the possibility of including a donation to a cause or charity with which they identify.

According to data from 2015, only 1% of wills made in Spain included a charitable bequest.

Institutional news
<p>Eduard Batlle, head of the Colorectal Cancer laboratory at IRB Barcelona</p>
10 Sep 2018

IRB Barcelona has been awarded two ERC PoC grants to optimise and validate tools with potential clinical applications.

Angel R. Nebreda’s project seeks to develop treatments to reduce the cardiotoxicity caused by chemotherapy.

Eduard Batlle’s project will build a biobank of mouse tumour organoids with the aim to contribute to the treatment of patients with advanced colon cancer.