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Degrading proteins to divide cells

2 Sep 11


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The news section of the chemistry website Quí echoes the latest discoveries by the research group led by Ferran Azorín at the Institute for Research in Biomedicine (IRB Barcelona), and published recently in Current Biology. Performed in Drosophila, the study reveals that the levels of the centromeric histone CenH3 in Drosophila, which are crucial for the correct function of the centromere during cell division, are tightly regulated through degradation in the proteasome.

About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).