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Degrading proteins to divide cells

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The news section of the chemistry website Química.es echoes the latest discoveries by the research group led by Ferran Azorín at the Institute for Research in Biomedicine (IRB Barcelona), and published recently in Current Biology. Performed in Drosophila, the study reveals that the levels of the centromeric histone CenH3 in Drosophila, which are crucial for the correct function of the centromere during cell division, are tightly regulated through degradation in the proteasome.

About IRB Barcelona

The Institute for Research in Biomedicine (IRB Barcelona) pursues a society free of disease. To this end, it conducts multidisciplinary research of excellence to cure cancer and other diseases linked to ageing. It establishes technology transfer agreements with the pharmaceutical industry and major hospitals to bring research results closer to society, and organises a range of science outreach activities to engage the public in an open dialogue. IRB Barcelona is an international centre that hosts 400 researchers and more than 30 nationalities. Recognised as a Severo Ochoa Centre of Excellence since 2011, IRB Barcelona is a CERCA centre and member of the Barcelona Institute of Science and Technology (BIST).