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IRB Barcelona opens new door to study cellular protein machinery

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30 Jan 17

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“El Temps” magazine publishes an extensive report about the research on protein nanomachines (also called protein complexes) —the structures responsible for performing cell functions—, headed by Oriol Gallego, research associate with the Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona.

The study, which also involved PhD student Irene Pazos, combines genetic engineering, super-resolution microscopy and biocomputation to allow researchers to see for the first time in 3D the protein machinery inside living cells. 

Published in the journal Cell, this work unveils key functional features of an assembly of proteins that is vital for animals and plants.

Link to El Temps

About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 28 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).