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Key protein in cilia formation identified

24 Aug 15

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The digital edition of the “El Periódico de Catalunya” newspaper, as well as other digital media, has published an article published in Current Biology about the discovery made by researchers led by Cayetano González, group leader of the Cell Division Laboratory at IRB Barcelona. The study shows that the absence of the protein Centrobin in cell centrioles determines their ability to form a cilium. The absence or malfunction of the cilia causes many diseases in humans (ciliopathies).

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About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).