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Research into Alzheimer’s disease. Amyloid protein aggregates may perforate the neuronal cell membrane

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Natalia Carulla
Research Associate
Tel.+34 93 40 37123

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Press & Communications Section Head
Tel.+34 93 40 37255

Extensive impact of Natàlia Carulla’s work at IRB Barcelona on a new method through which to study neuron death in Alzheimer’s disease.

Published in PNAS, the study addresses the effects of an amyloid protein aggregate that has the capacity to perforate the neuronal cell membrane—a process that may cause the toxicity of these aggregates and that could be validated as a therapeutic target.

Link to La Vanguardia:
http://www.lavanguardia.com/vida/20160913/41277475210/describen-como-preparar-un-agregado-que-perfora-la-membrana-de-las-neuronas.html

Link to Jano (Elsevier):
http://www.jano.es/noticia-nueva-estrategia-entender-muerte-neuronal-26674

About IRB Barcelona

The Institute for Research in Biomedicine (IRB Barcelona) pursues a society free of disease. To this end, it conducts multidisciplinary research of excellence to cure cancer and other diseases linked to ageing. It establishes technology transfer agreements with the pharmaceutical industry and major hospitals to bring research results closer to society, and organises a range of science outreach activities to engage the public in an open dialogue. IRB Barcelona is an international centre that hosts 400 researchers and more than 30 nationalities. Recognised as a Severo Ochoa Centre of Excellence since 2011, IRB Barcelona is a CERCA centre and member of the Barcelona Institute of Science and Technology (BIST).