Researchers describe a key protein in the infection that causes glandular fever

Structure of the portal proteins of Epstein-Barr virus. Cristina Machón, IRB Barcelona.

Structure of the portal proteins of Epstein-Barr virus. Cristina Machón, IRB Barcelona.


The newspaper La Vanguardia and the specialised journals SINC and Diario Médico, among other media, have published articles on two studies performed by researchers at IRB Barcelona and the Molecular Biology Institute of Barcelona (IBMB-CSIC). The studies describe the structure of the portal protein of the Epstein-Barr virus and bacteriophage T7, which is crucial for infection by these two viruses. Although the Epstein-Barr virus, which causes glandular fever (also known as mononucleosis) and various kinds of cancer, is one of the most common viruses found in humans, there is still no treatment available. “Understanding the structure of the portal protein could be useful for the design of drugs for the treatment of herpesvirus infections such as Epstein-Barr,” says Miquel Coll, researcher at IRB Barcelona and CSIC. Published in Nature Communications, the study is a collaboration with the National Centre for Biotechnology (CNB-CSIC) and the University of Oxford (UK).

Link to La Vanguardia

Link to SINC

Link to Diario Médico