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Senolytic compounds may be able to reverse the effects of aging

12 Mar 20

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The newspaper Entre Mayores has published an interview with Manuel Serrano, ICREA researcher and head of the Cell Plasticity and Disease Lab at IRB Barcelona, about senolytic compounds, which may be able to reverse the effects of aging.

Experimental research on animals to date has demonstrated that tissue health can be enhanced by eliminating senescent cells. This discovery has led many research groups to search for compounds with the capacity to selectively kill these cells. Although still in experimental stages, some drugs can remove these cells and, consequently, improve age-associated health conditions. “These drugs would in a certain way complete the tissue repair process by removing senescent cells,” says Serrano. 

Link to: Entre Mayores 


 

About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).