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Senolytic compounds may be able to reverse the effects of aging



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The newspaper Entre Mayores has published an interview with Manuel Serrano, ICREA researcher and head of the Cell Plasticity and Disease Lab at IRB Barcelona, about senolytic compounds, which may be able to reverse the effects of aging.

Experimental research on animals to date has demonstrated that tissue health can be enhanced by eliminating senescent cells. This discovery has led many research groups to search for compounds with the capacity to selectively kill these cells. Although still in experimental stages, some drugs can remove these cells and, consequently, improve age-associated health conditions. “These drugs would in a certain way complete the tissue repair process by removing senescent cells,” says Serrano. 

Link to: Entre Mayores 


About IRB Barcelona

The Institute for Research in Biomedicine (IRB Barcelona) pursues a society free of disease. To this end, it conducts multidisciplinary research of excellence to cure cancer and other diseases linked to ageing. It establishes technology transfer agreements with the pharmaceutical industry and major hospitals to bring research results closer to society, and organises a range of science outreach activities to engage the public in an open dialogue. IRB Barcelona is an international centre that hosts 400 researchers and more than 30 nationalities. Recognised as a Severo Ochoa Centre of Excellence since 2011, IRB Barcelona is a CERCA centre and member of the Barcelona Institute of Science and Technology (BIST).