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Ubiquitin receptors regulate gene expression

4 May 15




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Various media have published the discovery made by the team led by Ferran Azorín, group leader at IRB Barcelona and CSIC research professor, and recently published in the journal Nature Communications. This laboratory has found that the dDsk2 protein, in addition to degrading proteins, also plays a key role in regulating gene expression. Ferran Azorín’s group will start a study on the relationship between dDsk2 mutations and neurodegenerative diseases, such as Alzheimer’s disease.

About IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).