Several media, including Quo Magazine, have echoed the research headed by Ferran Azorín, CSIC research professor and group leader of the Chromatin Structure and Function laboratory at IRB Barcelona. The study reveals why histone 1 is a major protection factor against genomic instability and a vital protein for the organism.
Published in Nature Communications, this work explains for the first time that the suppression of histone 1 causes cell damage and genomic instability (DNA damage).
Link to Quo
Selected media mentions
Link to SINC Agency
Link to Madridmasde
A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.
Published in Nature Cell Biology, the study is a collaboration between a biomedical lab and a computational lab at IRB Barcelona.
Most solid tumours with metastatic potential show a high degree of chromosomal instability.
A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour.
The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour.
La Vanguardia reports on a recent study published by Marco Milán’s lab in the journal Developmental Cell. On the basis of their findings in the fruit fly (Drosophila melanogaster), the scientists have concluded that the chromosomal instability characteristic of tumours can promote invasive behaviour in cancer.
