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Structure of NCBD when it is not bound to any other protein
Scientific
Flexibility for functionality: the new dogma of protein structure
Individual intestinal stem cells generate spherical organoids when grown in lab-plates (upper pannel). Under the microscope (lower pannel), these organoids reveal to be composed mostly by undiferentiated and proliferative cells, the intestinal stem cells
Scientific
A recipe for isolating and growing human intestinal stem cells at the lab bench
Interneuron obtained from an engineered mouse lacking the malin gene (in green) and showing the accumulation of Lafora bodies (in red).
Scientific
A mouse model brings new perspectives on Lafora disease
The localization of CenH3 protein in the centromere (upper panel) becomes inespecific along the chromosome (lower panel) when its regulated degradation is unpaired.
Scientific
Degrading proteins to divide cells
3D representation of the protein complex necessary for the activation of pho regulon genes in E. coli. The RNA polymerase protein (RNAP) binds to the transcriptional activator PhoB.
Scientific
Gene activation in 3D
Healthy intestinal crypts (upper image) maintain different cell types in their compartments. Cells located at the bottom of the crypt (lower image) in which ADAM10 is blocked (lower image) migrate to the upper cell compartment (cells in dark brown)
Scientific
Researchers discover the mechanism that determines cell position in the intestinal epithelium
The boundary between dorsal (D) and ventral (V) cell populations is smooth in wild type wing primordia (upper panel) and wiggly upon ectopic expression of bantam miRNA (bottom panel).
Scientific
On wings, compartments and missing links
Functional myocardium (S) from a normal mouse embryo (left). The absence of p38&#945. and p38&#946. proteins produces myocardium lacking the heart septal (right).
Scientific
New proteins required for correct embryonic development
irbbarcelona
Scientific
Embryos become "independent" at an early stage of development

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