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Montserrat Romero, Antonio Zorzano, David Sebastián and Juan Pablo Muñoz from the Complex Metabolic Diseases and Mitochondria Lab at IRB Barcelona. Source: Fundación BBVA
Institutional
Mitochondria, ageing and cancer
Manuel Serrano, head of the Cellular Plasticity and Disease laboratory at IRB Barcelona
Institutional
“Cell damage is happening in our bodies all the time”
Raúl Méndez and Eulàlia Belloc from the Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona
Scientific - Published in Nature
Discovery of a key protein involved in the development of autism
Structure of TGIF1, attached to DNA.
Scientific - Published in Nucleic Acids Research
Researchers discover a mechanism that inhibits the Smad signalling pathway
TLK inhibition leads to replication stress (green) and extensive DNA damage (red) in cultured cancer cells. Sandra Segura-Bayona, IRB Barcelona.
Innovation - Published in Science Advances
Key role identified for enzymes in DNA replication and sensitivity to chemotherapeutic drugs
Miquel Duran-Frigola, Associate Researcher at the Structural Bioinformatics and Network Biology lab, IRB Barcelona
Innovation - Published in Nature Communications
Acidic pH: the weakness of cancer cells
The figure shows two views, frontal and lateral, of the image obtained by CT of the lungs of a mouse with fibrosis (grey areas) before and after receiving nano-therapy directed at senescent cells. (Guillem Garaulet and Francisca Mulero, CNIO)
Innovation - Published in EMBO Molecular Medicine
Researchers design a nano-carrier to release drugs into damaged cells
Institutional
Mapping tumour development
Diversity is key: metagenomes from different enviroments can predict different types of gene functions (Graphic, F Supek, IRB Barcelona)
Scientific - Published in Microbiome
The depths of the ocean and gut flora unravel the mystery of microbial genes

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