High-ranking figures from the business and innovation sectors attended an event organised by IRB Barcelona and ESADE with the aim to highlight the importance of uniting all sectors of society against metastasis.
Advances in research into the immunological evasion, metabolism and latency of metastatic cancer cells allow the identification of potential targets to test therapies.
IRB Barcelona and the BBVA Foundation invite 20 renowned international scientists working in the field of cancer metastasis to a gathering in Barcelona.
After the scientific conference, IRB Barcelona and ESADE have organised a debate on how to translate scientific research to society.
This activity, developed in collaboration with BIST, will allow participants to learn how and why DNA is studied, and what genetic mutations are and how they relate to cancer.
Also, they will have the opportunity to use a reconstruction of a Light Sheet Microscope made of LEGO.
It seems the amino acid transporter SLC7A8/SLC3A2 plays an important role in this disease.
The study was coordinated by Manuel Palacín from IRB Barcelona and Virginia Nunes from IDIBELL.
"Vi per Vida", a charity run by sommelier Xavi Ayala, promotes social awareness of the importance of research.
The event will be held this Sunday, February 25 in Calella.
In spite of the difference between the cell functions responsible for giving rise to a tumour and for the metastasis of this same tumour, studies at IRB Barcelona using the fly Drosophila melanogaster reveal that some genes can drive both phenomena.
The Meet Our Scientists series presents Ernest Giralt, doctor of chemical sciences, who is the head of the Peptides and Proteins laboratory at IRB Barcelona.
In the video "The power of medicinal chemistry", Giralt highlights his interest in deciphering the language used by proteins to interact with each other.
A team headed by ICREA researcher Eduard Batlle discovers that immune system-stimulating treatments combined with a TGF-beta inhibitor are effective against colon cancer.
The researchers developed a mouse model that mimics advanced human colon cancer. This model has allowed them to study the immune system response for the first time.
GenStorm (“An integrated approach to visualize and model the spatial conformation of genes at the nanoscale level”), led by Pablo Daniel Dans (IRB Barcelona) and Marie Victoire Neguembor (CRG) is one of this projects.
Published in Nature Cell Biology (NCB), the study shows that the EXD2 protein is critical for the mitochondria, the cell’s powerhouses, to produce energy.
This protein was previously thought to be located in the cell nucleus and to be involved in DNA repair.
The results contribute to our basic understanding of mitochondria and suggest that EXD2 could be important for fertility and represent a potential target for cancer therapy.