Research Programmes / Core Facilities

Mouse Mutant Core Facility
Vacant position
Nick Berrow
Camille Stephan-Otto Attolini

Research Programmes

  • Cell and Developmental Biology
    More about Cell and Developmental Biology
  • Structural and Computational Biology
    More about Structural and Computational Biology
  • Molecular Medicine
    More about Molecular Medicine
  • Chemistry and Molecular Pharmacology
    More about Chemistry and Molecular Pharmacology
  • Oncology
    More about Oncology

Core Facilities & Services

Scientists at IRB Barcelona are supported by an extensive range of common core facilities that provide state-of-the-art technologies and scientific services. These facilities are a key asset for our research, allowing the Institute to obtain outstanding results. They are designed to incorporate the most novel technologies available and provide them to our researchers in the shortest time possible.

Interdisciplinary initiatives

IRB Barcelona's partnerships, with organisations in areas of mutual interest and expertise, aim to take advantage of the wealth of knowledge, resources and technologies so critical to advancing the field of biomedicine

Selected IRB Barcelona publications

Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O and Stracker TH.
Nat Cell Biol, 20 (2), 162-174 (2018)
Pluta R, Boer DR, Lorenzo-Díaz F, Russi S, Gómez H, Fernández-López C, Pérez-Luque R, Orozco M, Espinosa M and Coll M.
P Natl Acad Sci Usa, 114 (32), E6526-E653 (2017)
<p>Natcom</p>
Bayona-Feliu A, Casas-Lamesa A, Reina O, Bernués J and Azorín F.
Nat Commun, 8 (1), 283 (2017)
Solanas G, Peixoto FO, Perdiguero E, Jardí M, Ruiz-Bonilla V, Datta D, Symeonidi A, Castellanos A, Welz PS, Caballero JM, Sassone-Corsi P, Muñoz-Cánoves P and Benitah SA.
Cell, 170 (4), 678-692.e2 (2017)
Weill L, Belloc E, Castellazzi CL and Méndez R.
Nat Struct Mol Biol, 24 (8), 672-681 (2017)
Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA, Slebe F, Vilaseca M, Muñoz-Cánoves P and Guinovart JJ.
Cell Metab, 26 (1), 256-266.e4 (2017)
Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A and Claret M.
Cell Metab, 25 (6), 1390-1399. (2017)
Villanueva E, Navarro P, Rovira-Rigau M, Sibilio A, Méndez R and Fillat C.
Nat Commun, 8 14833 (2017)
Barriga FM, Montagni E, Mana M, Mendez-Lago M, Hernando-Momblona X, Sevillano M, Guillaumet-Adkins A, Rodriguez-Esteban G, Buczacki SJA, Gut M, Heyn H, Winton DJ, Yilmaz OH, Attolini CS, Gut I and Batlle E.
Cell Stem Cell, 20 (6), 801-816.e7 (2017)
Picco A, Irastorza-Azcarate I, Specht T, Böke D, Pazos I, Rivier-Cordey AS, Devos DP, Kaksonen M and Gallego O.
Cell, 168 (3), 400-412.e1 (2017)
Marcos E, Basanta B, Chidyausiku TM, Tang Y, Oberdorfer G, Liu G, Swapna GV, Guan R, Silva DA, Dou J, Pereira JH, Xiao R, Sankaran B, Zwart PH, Montelione GT and Baker D.
Science, 355 (6321), 201-206 (2017)
Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L and Benitah SA.
Nature, 541 (7635), 41-45 (2017)
Darré L, Ivani I, Dans PD, Gómez H, Hospital A and Orozco M.
J Am Chem Soc, 138 (50), 16355-1636 (2016)

News

<p>The overexpression of the gene Serpent in the Drosophila wing causes permanent overgrowth and it is sufficient to promote tumour development (Image: Kyra Campbell, IRB Barcelona)</p>
19 Feb 2018

In cancer research, there has been a tendency to differentiate between the genes responsible for tumour development and those that give rise to metastasis and to study these processes separately si

<p>Ernest Giralt</p>
14 Feb 2018

The chemist Ernest Giralt (Viladecans, 1948) is the head of the Peptides a

<p>The image shows a metastatic colon tumour infiltrated by the immune system (brown) after combined treatment with the TGF-beta inhibitor and immunotherapy.  (Author: Daniele Tauriello, IRB Barcelona)</p>
14 Feb 2018

In a short space of time, immunotherapy, that is to say therapies based on stimulating the immune system against cancer cells, has become a powerful approach to treat cancers such as melanoma and l

<p>Image shows the interaction between the MH1 domain of Smad4 in complex with the GGCGC site  (Maria Macias, IRB Barcelona)</p>
29 Jan 2018

The main TGF-β signal transduction mechanism is the Smad pathway. As transcription factors, Smad proteins interact directly with DNA.

Events

21 Feb
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Jose C. Reyes, Ph.D. Head of Department Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER). Sevilla, Andalusia, Spain.
22 Feb
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Sakari Vanharanta, Ph.D. MRC Cancer Unit, University of Cambridge, Cambridge, UK
23 Feb
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Prof. Michele De Luca, MD, PhD. Centre for Regenerative Medicine “Stefano Ferrari”, University of Modena and Reggio Emilia, Modena, Italy