Research Programmes / Core Facilities

Mouse Mutant Core Facility
Vacant position
Nick Berrow
Camille Stephan-otto Attolini

Research Programmes

  • Cell and Developmental Biology
    More about Cell and Developmental Biology
  • Structural and Computational Biology
    More about Structural and Computational Biology
  • Molecular Medicine
    More about Molecular Medicine
  • Chemistry and Molecular Pharmacology
    More about Chemistry and Molecular Pharmacology
  • Oncology
    More about Oncology

Core Facilities & Services

Scientists at IRB Barcelona are supported by an extensive range of common core facilities that provide state-of-the-art technologies and scientific services. These facilities are a key asset for our research, allowing the Institute to obtain outstanding results. They are designed to incorporate the most novel technologies available and provide them to our researchers in the shortest time possible.

Interdisciplinary initiatives

IRB Barcelona's partnerships, with organisations in areas of mutual interest and expertise, aim to take advantage of the wealth of knowledge, resources and technologies so critical to advancing the field of biomedicine

Selected IRB Barcelona publications

Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L and Benitah SA.
Nature (2016)
Rinaldi L, Datta D, Serrat J, Morey L, Solanas G, Avgustinova A, Blanco E, Pons JI, Matallanas D, Von Kriegsheim A, Di Croce L and Benitah SA.
Cell Stem Cell, 19 (4), 491-501 (2016)
Slebe F, Rojo F, Vinaixa M, García-Rocha M, Testoni G, Guiu M, Planet E, Samino S, Arenas EJ, Beltran A, Rovira A, Lluch A, Salvatella X, Yanes O, Albanell J, Guinovart JJ and Gomis RR.
Nat Commun, 7 11199 (2016)
Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y and Nebreda AR.
Nat Commun, 7 11084 (2016)
<p>Dev Cell</p>
Clemente-Ruiz M, Murillo-Maldonado JM, Benhra N, Barrio L, Pérez L, Quiroga G, Nebreda AR and Milán M.
Dev Cell, 36 (3), 290-302 (2016)
<p>Angew Chem Int Edit</p>
Oller-Salvia B, Sánchez-Navarro M, Ciudad S, Guiu M, Arranz-Gibert P, Garcia C, Gomis RR, Cecchelli R, García J, Giralt E and Teixidó M.
Angew Chem Int Edit, 55 (2), 572-5 (2016)
<p>Gastroenterology</p>
Calderone V, Gallego J, Fernandez-Miranda G, Garcia-Pras E, Maillo C, Berzigotti A, Mejias M, Bava FA, Angulo-Urarte A, Graupera M, Navarro P, Bosch J, Fernandez M and Mendez R.
Gastroenterology, 150 (4), 982-97.e30 (2016)
<p>Nature methods</p>
Ivani I, Dans PD, Noy A, Pérez A, Faustino I, Hospital A, Walther J, Andrio P, Goñi R, Balaceanu A, Portella G, Battistini F, Gelpí JL, González C, Vendruscolo M, Laughton CA, Harris SA, Case DA and Orozco M.
Nat Methods, 13 (1), 55-8 (2016)
Georgieva MV, Yahya G, Codó L, Ortiz R, Teixidó L, Claros J, Jara R, Jara M, Iborra A, Gelpí JL, Gallego C, Orozco M and Aldea M.
Nat Methods, 12 (10), 955-8 (2015)
Pavlovic M, Arnal-Estapé A, Rojo F, Bellmunt A, Tarragona M, Guiu M, Planet E, Garcia-Albéniz X, Morales M, Urosevic J, Gawrzak S, Rovira A, Prat A, Nonell L, Lluch A, Jean-Mairet J, Coleman R, Albanell J and Gomis RR.
Jnci-j Natl Cancer I, 107 (12), (2015)
Marjanović M, Sánchez-Huertas C, Terré B, Gómez R, Scheel JF, Pacheco S, Knobel PA, Martínez-Marchal A, Aivio S, Palenzuela L, Wolfrum U, McKinnon PJ, Suja JA, Roig I, Costanzo V, Lüders J and Stracker TH.
Nat Commun, 6 7676 (2015)
Kessler R, Tisserand J, Font-Burgada J, Reina O, Coch L, Attolini CS, Garcia-Bassets I and Azorín F.
Nat Commun, 6 7049 (2015)
<p>Nat Gen 2015</p>
Calon A, Lonardo E, Berenguer-Llergo A, Espinet E, Hernando-Momblona X, Iglesias M, Sevillano M, Palomo-Ponce S, Tauriello DV, Byrom D, Cortina C, Morral C, Barceló C, Tosi S, Riera A, Attolini CS, Rossell D, Sancho E and Batlle E.
Nat Genet, 47 (4), 320-329 (2015)
Prades R, Oller-Salvia B, Schwarzmaier SM, Selva J, Moros M, Balbi M, Grazú V, de La Fuente JM, Egea G, Plesnila N, Teixidó M and Giralt E.
Angew Chem Int Edit, 54 (13), 3967-72 (2015)

News

<p>Staining of mouse liver sections showing steatosis of the liver (fatty liver), with accumulation of fat, lipid droplets (in red), within cells. Cell nuclei stain blue (C. Maíllo, IRB Barcelona).</p>
17 Jan 2017

A team co-headed by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the IDIBAPS Biomedical Research Institute (part of the Hospital Clínic de Barcelona) has revealed the

<p>Examples of computationally designed proteins made of curved beta-sheets and helices forming cavities with different sizes and shapes (E.Marcos, IRB Barcelona-UW)</p>
13 Jan 2017

An international team of scientists led by the University of Washington (UW) in Seattle has deciphered key rules that govern how proteins form pocket-like structures that are essential for many key

<p>Ectopic wings upon ectopic activation of JAK/STAT (Carles Recasens-Alvarez and Ana Ferreira, IRB Barcelona)</p>
9 Jan 2017

Many of the secrets of life, such as how we become a certain size and shape, have been uncovered in studies performed over more than 100 years and involving animal models such as the fruit fly

<p>Despite the expanding repertoire of new anti-cancer agents, treatment failure remains a major challenge in the management of most advanced solid tumours, including breast cancer.</p>
20 Dec 2016

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic a

Events

25 Jan
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Teresa Juan Blanco, IRB Barcelona
25 Jan
Aula Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Martine Simonelig, Institut de Genetique Humaine, Montpellier
27 Jan
Fèlix Serratosa, Parc Científic de Barcelona
Speaker:
Francisco Real, MD, Ph.D. Epithelial Carcinogenesis Group, Centro Nacional de Investigaciones Oncológicas (CNIO) Madrid (Spain)