Biomedical Genomics news

<p>To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin for degradation. Francisco Martínez, IRB Barcelona.</p>
2 Dec 2019

Published in the journal Nature Cancer, the study analyses how genetic alterations in tumour cells prevent the correct degradation of the proteins involved in tumour development and growth, thereby leading to abnormal cell behaviour.

A machine-learning model has allowed the scientists to obtain the most extensive annotation of the ubiquitin-mediated protein degradation system.

The analysis proposes a potential new clinical approach for cancer through the inhibition of oncoproteins with impaired degradation systems.

<p>Erika Lopez, IRB Barcelona.</p>
25 Nov 2019

The newspaper La Tribuna de Albacete has interviewed IRB Barcelona researcher Erika López Arribillaga about a grant awarded to her on 24 September by the Spanish Association Against Cancer (AECC). López Arribillaga’s project aims to unravel the long-term effects of some chemotherapy treatments on colorectal cancer patients. 

 

Link to La Tribuna de Albacete

 

 

<p>Researchers at IRB Barcelona have identified these genetic footprints produced by some cancer treatments and have for the first time been able to calculate the genetic toxicity of some of these treatments. Claudia Arnedo, IRB Barcelona.</p>
25 Nov 2019

The newspapers El MundoLa Vanguardia and Diari Ara, the TV station TV3 and the radio stationsCatalunya Ràdio andRAC1, among other media, have echoed on a study by the Biomedical Genommics lab, headed by Núria López, published in Nature Genetics. The study has for the first time determined the genetic mutations caused by various therapies used to treat cancer. “Studying the DNA damage caused by chemotherapies in patients’ cells is the first step towards understanding the relation between these mutations and the long-term side effects of these treatments,” says Oriol Pich, PhD student at IRB Barcelona and first author of the...

<p>Researchers at IRB Barcelona have identified these genetic footprints produced by some cancer treatments and have for the first time been able to calculate the genetic toxicity of some of these treatments. Claudia Arnedo, IRB Barcelona.</p>
19 Nov 2019

Scientists at IRB Barcelona determine the genetic alterations in the cells of cancer patients caused by the main cancer therapies.

This is an important step towards understanding the long-term side effects and optimizing treatments against cancer.

The results have been published in the journal Nature Genetics.

<p>El presidente de la AECC, Ignacio Muñoz, durante la ceremonia de entrega de las ayudas.</p>
30 Sep 2019

Salvador Aznar-Benitah has received a grant in the AECC Project category.

Two postdoctoral fellowships have been awarded to researchers Magdolna Djurec and Erika López Arribillag.

<p>Press conference at IRB Barcelona, presenting the #MetastasisChallenge</p>
19 Mar 2019

Catalunya Ràdio, El Punt Avui, Expansión Catalunya, Europa Press, EFE, among other media, have published an article about the launch of the #MetastasisChallenge campaign. Through this initiative, the Institute for Research in Biomedicine (IRB Barcelona) calls society to action to support research into metastasis—the main cause of death from cancer—by raising €5 M over the next four years.

Link to El Punt Avui

Link to...

<p>Press conference at IRB Barcelona, presenting the #MetastasisChallenge</p>
19 Mar 2019

Through the campaign called #MetastasisChallenge, the centre aims to raise €5 M over the next four years.

Metastasis is responsible for 90% of deaths from cancer, and this campaign aims to rally social support for research in order to speed up discoveries.

<p>Núria López-Bigas, head of the Biomedical Genomics Lab at IRB Barcelona</p>
11 Feb 2019

On the occasion of the "International Day of Women and Girls in Science", the web portal Núvol has published an article highlighting 25 women researchers who are developing leading projects in science and technology in Spain. One of them is Núria López-Bigas, head of the Biomedical Genomics Laboratory at IRB Barcelona, who studies cancer from a genomic perspective and develops computational methods to identify the genetic mutations responsible for the development of tumours.

Link to Núvol

<p>Sofie Vanthournout, director of Sense About Science</p>
27 Dec 2018

IRB Barcelona hosts the workshop “Standing up for Science”, for young researchers interested in public outreach activities. 

Organised by the European organisation Sense About Science, the workshop involved more than 50 researchers, including members of IRB Barcelona, from various countries.

<p>The 2019 “Recerca en Directe” fair will be held from 6-9 March at the CosmoCaixa</p>
4 Dec 2018

The Institute will be giving a workshop entitled “Deciphering the code of cancer”