Cellular Plasticity and Disease news

<p>Manuel Serrano</p>
30 Jul 2020

The ERC Proof of Concept grant offers 150,000 euros to fund the development of new drugs against fibrosis within 18 months.

The SENFIB project aims to eliminate senescent cells. These are damaged cells which, if not destroyed by the immune system, can give rise to aging-related diseases such as idiopathic pulmonary fibrosis and chronic kidney disease.

To achieve this aim, the project makes use of senolytics, molecules which lead to the selective death of these cells and have produced positive results in animal models.

<p>Manuel Serrano, head of the Cell Plasticity and Disease Laboratory at IRB Barcelona</p>
12 Mar 2020

Manuel Serrano, ICREA researcher and head of the Cell Plasticity and Disease Group at IRB Barcelona, has been interviewed on Radio 4´s programme De boca a orella. The interview was about ways to measure biological age. The scientist says that one of the techniques receiving most attention is the epigenetic clock. He goes on to explain that this is a “clock” present in our blood and that, combined with the study of other factors such as telomeres (the structures that form at the ends of chromosomes),  it serves to measure biological age. He goes on to say, ““Chromosomes are the structures in which lineal DNA is found. We have 23 chromosomes and their ends hold a repeated...

<p>Manuel Serrano, researcher at IRB Barcelona</p>
6 Mar 2020

The programme “El Balcó” broadcasted by the radio channel Cadena Ser has interviewed Manuel Serrano, ICREA researcher and head of the Cell Plasticity and Disease Lab at IRB Barcelona. The interview was about regenerative medicine, a kind of medicine that attempts to understand tissue regeneration mechanisms.  “The regenerative process is well described and it is known what happens. But there is little information about the mechanisms, genes and proteins involved,” says Serrano The researcher insists that “it is necessary to understand the process at the molecular level and to be able to manipulate it via pharmacological means. In processes involving defective repair,...

<p>Manuel Serrano, researcher at IRB Barcelona</p>
4 Mar 2020

The journal The Scientist has published an interview with Manuel Serrano, ICREA researcher and head of the Cell Plasticity and Disease Lab at IRB Barcelona, about studies into cell aging done in recent years. In the 1950s, the scientist Leonard Hayflick did a series of studies in which he demonstrated that cells enter what is known as a “senescent” state. Initially, the scientific community rejected this concept, considering it irrelevant for living organisms. However, work done in later decades by researchers like Manuel Serrano has revealed the importance of cell senescence.  Serrano has observed that when cells are exposed to stress stimuli that would normally lead...

<p>Manuel Serrano, ICREA researcher at IRB Barcelona, during his talk at the Barcelona Biomed Conference.</p>
27 Nov 2019

The newspapers El País and ABC, among other media, have echoed on the last Barcelona Biomed Conference, called “Immunotherapy beyond cancer. A cure for age-related diseases”which was held from 18 to 20 November.  “Immunotherapy is still very experimental, but we believe that in the future it could be beneficial for the treatment of diseases such as Alzheimer’s, Parkinson’s and pulmonary and renal fibrosis,” says Manuel Serrano, ICREA researcher at IRB Barcelona and co-organiser of the conference together with the scientist Guido Kroemer, from the Centre de Recherche des Cordeliers (Paris). As in previous events, this conference was organised by IRB Barcelona...

<p>Manuel Serrano, ICREA researcher at IRB Barcelona, during his talk at the Barcelona Biomed Conference.</p>
21 Nov 2019

When you hear the word ‘immunotherapy’, the first thing that comes to mind is that it is a highly effective treatment for cancer. But could it also be the solution or hope for other conditions? 

This was precisely the subject addressed at the Barcelona Biomed Conference “Immunotherapy beyond cancer. A cure for age-related diseases”an event organised by the Institute for Research in Biomedicine (IRB Barcelona) from 18 to 20 November that brought together more than 100 scientists.

Over 3 days, researchers from all over the world have emphasized the potential of this new therapy for other applications. In this regard, Manuel Serrano...

<p>Manuel Serrano, IRB Barcelona.</p>
18 Sep 2019

In the context of the Longevity World Forum, which will be held on 14 and 15 November in Barcelona, the specialised journal Acta Sanitaria has published an interview with IRB Barcelona researcher Manuel Serrano. “We want to understand how tissues respond to damage (and the word damage includes aging, degenerative diseases and cancer),” says the scientist.

Link to Acta Sanitaria

 

<p>Manuel Serrano, IRB Barcelona.</p>
18 Sep 2019

The newspapers ABC and La Vanguardia, and the radio station COPE, among other media, have reported on the international Geroscience gathering, which was held on 13 and 14 September in Madrid. This is the first time that this event has been hosted in Europe and, on this occasion, IRB Barcelona researcher Manuel Serrano was one of the organisers. Geroscience aims to increase knowledge of the aging process and to disseminate research breakthroughs in this field. “Science and research are not pursuing immortality but aim to improve the treatments of typical aging-associated diseases, with a focus on being able to...

<p>Marta Kovatcheva, postdoctoral researcher at IRB Barcelona</p>
1 Mar 2019

20 Minutos, La Rioja and Europa Press have published an article on the funding received by IRB Barcelona scientist Marta Kovatcheva for her studies on how to prevent lung cancer relapse after treatment. Thanks to the IV Women's Race organised by the Spanish Association Against Cancer (AECC) in La Rioja, her research will receive 160,000 euros.

Link to 20 Minutos

Link to La Rioja

Link to...

<p>100tífiques. Source: FCRI</p>
6 Feb 2019

The Barcelona Institute of Science and Technology (BIST) will be bringing together 100 female researchers and technologists in a training and networking session next Thursday, 7 February, at the Barcelona Science Park. IRB Barcelona will be participating in this event.

The gathering is devoted to the preparation of the talks that the scientists will be giving around Catalonia on the International Day of Women and Girls in Science (11 February) and to ‘fostering a sense of community’ to reinforce the role of women as scientific and social leaders.

The mayor of Barcelona, Ada Colau, will be opening the event, which forms part of the Biennial City and Science Programme.