It is a factor that has been conserved through evolution, from plants to mammals
RPAP1 regulates the activity of RNA polymerase II by means of its interaction with gene transactivators
La Vanguardia, La Razón, Diario Médico, among other media, have highlighted the recognition given to Manuel Serrano, ICREA Research professor and group leader of the Cellular Plasticity and Disease Lab at IRB Barcelona, for his work "Tissue damage and senescence provide critical signals for reprogramming cellular in vivo". He has been distinguished with the Severo Ochoa Prize for Biomedial Research. It is a project financed by CaixaImpulse, a program of "la Caixa" Bank Foundation and Caixa Capital Risc.
The Ferrer Research Foundation acknowledges the various perspectives of his research into cancer and aging.
The academic year began with the arrival of 11 new students to IRB Barcelona’s International PhD Programme—among them Elena Meléndez Esteban (b. Barcelona, 1993), the recipient of the first "IRB Barcelona Futur” PhD fellowship. This fellowship has come about from the campaign with the same name launched by the institute in December 2016 to increase public awareness of the importance of biomedical research and PhD training. “So many people have shown such generosity in supporting the PhD training of a young researcher whom they have never met,” says Elena.
Diario Médico explains, through IRB Barcelona researcher Cristina Pantoja, the research conducted in regenerative medicine in the Cellular Plasticity and Disease laboratory. The specialized newspaper goes on to describe how the incorporation of Manuel Serrano’s lab to IRB Barcelona in May was made possible thanks to the joint effort of ICREA of the Generalitat de Catalunya and the Obra Social "la Caixa".
The “IRB Barcelona Futur” fellowship is funded by donations given to the permanent fundraising campaign “Futur”, which supports the training of young scientists.
The first awardee is a 24-year-old student who graduated in Biomedicine and holds a Master’s from the University of Utrecht and the Gurdon Institute in Cambridge Cambridge.
Scientific American responds to an article originally published in Nature on senescent cells (which have lost the ability to divide) and their impact on premature aging. The author cites ICREA researcher Manuel Serrano, at IRB Barcelona, who has studied the phenomenon of senescence for more than 25 years.
Link to Scientific American
In an extensive article, the channel of science and technology news Néxt/VózPopuli relates how tycoons in Silicon valley are attempting to buy eternal youth.
Manuel Serrano, researcher at IRB Barcelona, and other experts on ageing consulted, consider that there is an investment “bubble” in the anti-aging research field. “It’s great that wealthy people believe that ageing is a condition that can be treated,” he says. “We are starting to get spectacular results in mice and I think there is a sufficient scientific basis for optimism. If I were rich I would also be investing in this,” he concludes.
Read the article here:...
La Razón devotes an article to the research performed by Manuel Serrano at IRB Barcelona’s Cellular Plasticity and Disease laboratory, promoted by the ICREA programme and the Obra Social "la Caixa".
"Our goal is to find experimental compounds that have the capacity to kill the damaged cells that are generated in everyone and that, beyond a given a level, can lead to disease," explains Manuel Serrano. And he adds, "nowadays there are compounds capable of killing damaged cells while causing minimal deterioration of healthy cells”.
'El Balcó', a programme on Cadena SER radio, interviews Manuel Serrano, group leader of the Cellular Plasticity and Disease laboratory at IRB Barcelona. During the interview, the ICREA researcher explains what his goals are in regenerative medicine.
"Regenerative medicine seeks to generate new cells. For example, in diabetes, the pancreas lacks cells that produce insulin. What we are trying to do is to generate cellular plasticity in the cells of the pancreas so that they are able to generate cells that produce insulin," explains Manuel Serrano.