Development and Growth Control Laboratory news

<p>Marco Milán.</p>
15 Feb 2017

The “Meet Our Scientists” video entitled “Our relative the fly” presents the research performed by Marco Millán on the fruit fly.

He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.

13 Jan 2017

"Gaceta Médica” devotes an article to the study headed by ICREA Professor Marco Milán. Published in Nature Communications, the study identifies a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila.

Link to Gaceta Médica

<p>Ectopic wings upon ectopic activation of JAK/STAT (Carles Recasens-Alvarez and Ana Ferreira, IRB Barcelona)</p>
9 Jan 2017

Researchers at IRB Barcelona identify a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila.

Published in Nature Communications, the study paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.

9 Jan 2017

Various media report on the study headed by ICREA Professor Marco Milán, leader of the Development and Growth Control Lab at IRB Barcelona. The study discloses a new signal that participates in the specification and growth of fruit fly (Drosophila melanogaster) wings.

Published in Nature Communications, this work paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.

Link to ...

<p>The "Create your own monster" workshops aims to teach children about the genetic code</p>
14 Jun 2016

IRB Barcelona is to hold three workshops for all kinds of public

10 Feb 2016

The health-specialized site Jano.es has dedicated an article to a new study published in Developmental Cell by Marco Milán, ICREA researcher and leader of the Development and Growth Control Laboratory at IRB Barcelona. The paper explains how protective cellular mechanisms triggered by aneuploidy could cause tumours.

<p>In the picture, precursor cells of fly wing tissue, labelled for various proteins. This fly model has been used to perform experiments addressing the relationship between chromosome instability, aneuploidy, and tumorigenesis (Lara Barrio, IRB Barcelona)</p>
9 Feb 2016

Aneuploid cells—that is to say those with an abnormal number of chromosomes—are found in most human tumours.

A study conducted at IRB Barcelona on the fly Drosophila reveals how surviving aneuploid cells favour tumour development.

12 Jan 2016

Diari de Girona has published a column on a new mechanism involved in tissue regeneration, discovered recently. The study, published in PLOS Genetics, was conducted by the Department of Genetics at the University of Barcelona in collaboration with the group led by Marco Milán, ICREA researcher and leader of the Development and Growth Control Laboratory group at IRB Barcelona. This new mechanism is a significant advance in understanding how tissue regeneration works, and indicates that antioxidants may have a negative effect during the early stages of this process.

31 Aug 2015

Various media, including the newspaper “El Punt Avui”, have echoed the study published in PLoS Biology by Marco Milán, ICREA researcher and group leader of the Development and Growth Control Laboratory at IRB Barcelona, and Ana Ferreira, PhD student from the same laboratory. The researchers have explained the way tumour suppressor genes regulate the growth of cells surrounding the tumour.

<p>Depletion of the PTEN tumour suppressor gene induces tissue overgrowth and reduces the growth of the neighbouring cell population in Drosophila wing primordia (Image: Marco Milán’s Lab).</p>
28 Aug 2015

Researchers at IRB Barcelona unravel a role for tumour suppressor genes in restricting the growth of neighbouring cell populations.

The study, published yesterday in PLoS Biology, might have implications for understanding the early events of tumorigenesis and the selection of the tumour-initiating cells.