Molecular Modelling and Bioinformatics news

27 Jul 2015

Combination of two strong denaturants of DNA leads to stabilization of the structure

An unexpected finding that opens new fields to the biotechnological use of DNA

22 Jul 2015

A study, published today in the journal Nature, marks a milestone in the understanding of chronic lymphocytic leukemia (CLL)

CLL is the most frequent leukemia with more than 12,000 new cases diagnosed in Europe every year

IRB Barcelona group leader Modesto Orozco participated in the study as he is involved with the International Cancer Genome Consortium (ICGC)

14 Jul 2015

The newspaper “El Periódico de Catalunya” has echoed the award ceremony of the 77 grants given by the “Obra Social La Caixa” foundation to support doctoral students. This grant programme aims to retain Spanish students and attract international students with talent for research, both for Spanish universities and Severo Ochoa centres. In this edition, IRB Barcelona students Jürgen Walther, Craig Donoghue, Elzbieta Szulc, and Lada Murcia received these awards.

6 Jul 2015

The trilingual magazine of the city of Barcelona, Barcelona Metropolis, dedicates its leading article and an extensive report to the biomedicine conducted in Barcelona. Various articles in this edition address topics related to this discipline, ranging from biomedicine as a business model and associated research fields, such as biomedical chemistry or big data, to key institutions such as the Catalan Institution for Research and Advanced Studies (ICREA).

IRB Barcelona is well represented in the magazine, with references and statements by Joan Guinovart, director of the institute, Patrick Aloy, Eduard Batlle, Natàlia Carulla, Ernest Giralt, Modesto Orozco, and Xavier Salvatella,...

17 Dec 2014

ELIXIR coordinates the storage, access and development of the software needed to understand biological data

Six institutions coordinated through the INB, whose central node is hosted at the CNIO, will participate in the European infrastructure 

<p>Researchers have experimentally and theoretically determined for the first time an important property of DNA that has remained unknown until now - its dielectric constant. This opens the way to a realistic computational description of DNA...</p>
18 Aug 2014

The electric polarizability of DNA is a fundamental property that directly influences its biological functions. Despite the importance of this property, however, its measurement has remained elusive so far.

In a study published in PNAS today, researchers at Barcelona’s Institute for Bioengineering of Catalonia (IBEC) led by Laura Fumagalli, senior researcher at IBEC and lecturer at the University of Barcelona, and their collaborators at the Institute for Research in Biomedicine (IRB) and at Barcelona Supercomputing Center (BSC), and at Centro Nacional de Biotecnologia (CNB-CSIC) and IMDEA Nanociencia in Madrid, describe how they have found a way to directly measure DNA electric polarizability – represented by its dielectric constant, which indicates how a material reacts to an applied electric field – for the first time ever.

12 Jun 2014

Genetic Engineering & Biotechnology News (GEN) devotes a news item to the recent study by IRB Barcelona scientists Xavier Salvatella and Modesto Orozco.

Published in Nature Communications, the study reports the team's discovery that the motions of various parts of proteins, although physically far apart, are correlated. Such findings hint at another way to think about drug development.

Read the news in...

<p>Xavier Salvatella leads the Laboratory of Molecular Biophysics (Battista/Minocri, IRB Barcelona)</p>
12 Jun 2014

A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.

Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.

<p>Math4Life is a new programme to train biostatisticians</p>
12 May 2014

This initiate is aimed at young undergraduate students and graduates in statistics, mathematics, informatics, and bioinformatics interested in the biosciences.

Maths4Life involves tutored summer training placements in labs working in cancer, network biology, molecular modelling and biostatistics.

9 Mar 2014

Researchers at IRB, Jordi Duran and Modesto Orozco, have been consulted by the journalist Cristina Sáez for an article on memory for the Magazine of "La Vanguardia".

Jordi Duran, associate researcher with Joan Guinovart's group, studies the implications of glycogen on memory function and learning. Modesto Orozco, an expert in biocomputation, is one of the researchers involved in the Human Brain Project, the European initiative that seeks to simulate how the brain works within the next 10 years.

Read the article in La Vanguardia (...