Results about: cancer

Researchers at IRB Barcelona identify a possible therapeutic target for Kennedy´s disease and prostate cancer

Activation of the chaperone protein Hsp70 leads to a decrease in the formation of androgen receptor aggregates, which give rise to muscular atrophy in patients with Kennedy´s disease, a rare condition for which no treatment is available.

The results may also be useful in the search for a treatment for castration-resistant prostate cancer, a disease that causes 30,000 death a year in Europe and for which there is no treatment.

The study, which has been published in Nature Communications, is a collaboration with the University of California San Francisco and the University of Michigan. 

Researchers identify a new biomarker for personalised treatments against cancer

Many treatments against cancer, such as TRAIL, aim to trigger a type of cell death known as apoptosis.

A team at IRB Barcelona, headed by Antonio Zorzano, has demonstrated that the protein TP53INP2 induces apoptosis in chemotherapy treatments.

IRB Barcelona calls society to action in the fight against metastasis

Through the campaign called #MetastasisChallenge, the centre aims to raise €5 M over the next four years.

Metastasis is responsible for 90% of deaths from cancer, and this campaign aims to rally social support for research in order to speed up discoveries.