Results about: mitochondria
Age-related metabolic diseases have increased to epidemic proportions in all industrialized countries.
Our research addresses the evolution of the protein synthesis machinery, the molecular interactions that regulate it, and the biomedical applications that can be derived from its study. Our research projects are focused around the biology of transfer RNA (tRNA).
A study reveals that the essential protein SLIMP coordinates protein synthesis and DNA replication in mitochondria
The team headed by ICREA researcher, Lluís Ribas, has published a study in Cell Report describing a functional network that coordinates protein synthesis and DNA replication in animal mitochondria.
These findings contribute to our understanding of the mechanisms involved in mitochondrial dysregulation associated with diseases such as MELAS and MERRF and may help to identify new therapeutic approaches.
A project headed by Antonio Zorzano at IRB Barcelona has been awarded funding from the BBVA Foundation to explore a possible link between ageing and cancer.
Called MitoFuss, the project focuses on the mitochondrial protein Mitofusin 2.
A study performed at IRB Barcelona supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation.
Researchers discover activators of a potential therapeutic target for the treatment of patients with diabetes and insulin resistance
A team headed by Antonio Zorzano at IRB Barcelona has identified activators of the mitochondrial protein Mitofusin 2 for the treatment of type 2 diabetes.
The protein is a key regulator of many mitochondrial functions, as well as of the cell as a whole.
The 2017 IRB Barcelona Alumni of Excellence Award has gone to Marc Liesa, who obtained his PhD in 2008 in Antonio Zorzano’s Complex Metabolic Diseases and Mitochondria Laboratory. The award, established in 2016, acknowledges the excellence of former IRB Barcelona scientists and is given with the support of Eppendorf. Liesa visited the Institute on 5 May to receive the distinction. He talks about his science and shares some secrets of his success.