Results about: stem cell

<p>Batlle</p>

Colorectal Cancer (CRC) is one of the leading causes of death by cancer worldwide. Most colorectal tumors develop as benign lesions but a small proportion progress to more malignant stages when the appropriate alterations in oncogenes and tumour suppressor genes occur.

Exploring new frontiers in colorectal cancer research

ICREA research professor Eduard Batlle is featured in the “Meet Our Scientists” video entitled “Deconstructing colon cancer”.

The video presents IRB Barcelona's Colorectal Cancer Laboratory research, which is devoted to understanding the behaviour of colon tumours and propose new cures for patients.

“No matter how experienced you are, you always have to think that what you don’t know is more than what you do know”

Peter Jung was Postdoctoral Fellow in Eduard Batlle’s Colorectal Cancer lab between 2009 and 2015. Now he is Principal Investigator at the Institute of Pathology Ludwig-Maximilians-Universität in Munich. This institute is a partner site of the DKTK Cancer Consortium, coordinated by the German Cancer Research Center (DKFZ). “Life and science are an on-going learning process with new challenges to encounter with every new project,” he says.

Two wings against cancer

In the conference Drosophila as a model in cancer”, to be held from 15 to 17 June in Barcelona, IRB Barcelona and the BBVA Foundation bring together a select group of leading scientists that use the fruit fly for cancer research.

This fly can be used to study specific types of tumour, ranging from leukaemia to brain tumours, and complex processes such as metastasis or the wasting syndrome (extreme muscle weakness) associated with cancer. In addition, Drosophila has proved to be an excellent tool for drug screening in vivo.

Nobert Perrimon is among the invited speakers. From his lab at Harvard, he has performed one of the largest screenings of molecules in flies in search of new anti-tumour applications of drugs that have already been approved by the FDA.

Special mention is also given to the participation of Sam Jackson, from the National Center for the Replacement, Refinement and Reduction of Animals in Research, a British organisation that promotes and supports the use of invertebrate models, such as Drosophila, for cancer research.