Results about: virus
Researchers describe a key protein for Epstein-Barr virus infection, which causes mononucleosis and cancer
Two studies by IRB Barcelona and IBMB-CSIC published in Nature Communications reveal the portal structure of the Epstein-Barr virus and bacteriophage T7.
No treatment is currently available for the infection caused by the Epstein-Barr virus, which, in addition to causing mononucleosis, leads to various types of cancer.
The studies were done in collaboration with CNB-CSIC and the University of Oxford.
Researchers decipher the structure and mechanism of action of a key complex involved in bacteriophage T7 infection
The study reveals the opening and closing mechanism of the portal protein during the maturation of the viral capsid, the structure that carries the genetic material of the virus.
The researchers have combined cryomicroscopy and crystallography techniques to study these viruses that infect bacteria.
IDIBAPS and IRB Barcelona researchers show the effectiveness of a new strategy to achieved genetically modified viruses that infect only tumor cells, thus preserving healthy tissues.
It is an innovative approach that exploits the different expression profiles of certain proteins between tumor and healthy cells, thus allowing the virus to infect only the former.