RTVE, the newspaper Heraldo de Aragón, and Diario Médico—the newspaper specialized in health—among other media, have echoed on a new algorithm, developed by researchers at IRB Barcelona in collaboration with the Centre for Genomic Regulation and the University of Radboud, that allows identification of those patients who are most likely to benefit from immunotherapy. Based on machine learning, the scientists have developed a tool that detects the genetic mutations that activate the immune system. This algorithm also identifies those people with certain hereditary diseases that would benefit from certain kinds of drug already on the market. The study was published in the journal Nature Genetics.
Link to RTVE
Link to Heraldo de Aragón
Link to Diario Médico
Published in the journal Nature Cancer, the study analyses how genetic alterations in tumour cells prevent the correct degradation of the proteins involved in tumour development and growth, thereby leading to abnormal cell behaviour.
A machine-learning model has allowed the scientists to obtain the most extensive annotation of the ubiquitin-mediated protein degradation system.
The analysis proposes a potential new clinical approach for cancer through the inhibition of oncoproteins with impaired degradation systems.
The newspaper La Tribuna de Albacete has interviewed IRB Barcelona researcher Erika López Arribillaga about a grant awarded to her on 24 September by the Spanish Association Against Cancer (AECC). López Arribillaga’s project aims to unravel the long-term effects of some chemotherapy treatments on colorectal cancer patients.
Link to La Tribuna de Albacete
The newspapers El Mundo, La Vanguardia and Diari Ara, the TV station TV3 and the radio stationsCatalunya Ràdio andRAC1, among other media, have echoed on a study by the Biomedical Genommics lab, headed by Núria López, published in Nature Genetics. The study has for the first time determined the genetic mutations caused by various therapies used to treat cancer.
