Several media, including Periodistas en Español, have highlighted the research performed by the group headed by ICREA Professor Marco Milan. The study reveals the ability of tumours of epithelial origin to grow in the absence of a tumour microenvironment. The researchers examined the growth of a tumour in the absence of adjacent cell populations like the immune system or mesenchymal cells.
Several media, including Quo Magazine, have echoed the research headed by Ferran Azorín, CSIC research professor and group leader of the Chromatin Structure and Function laboratory at IRB Barcelona. The study reveals why histone 1 is a major protection factor against genomic instability and a vital protein for the organism.
Published in Nature Communications, this work explains for the first time that the suppression of histone 1 causes cell damage and genomic instability (DNA damage).