Crucial gene in the development of the placenta discovered

<p>Cross sections of wild type or TLK2 deficient embryos stained for the proliferative marker Ki67. Embryos lacking TLK2 (left) appear morphologically normal but developmentally delayed. (S. Segura-Bayona, IRB Barcelona)</p>
Cross sections of wild type or TLK2 deficient embryos stained for the proliferative marker Ki67. Embryos lacking TLK2 (left) appear morphologically normal but developmentally delayed. (S. Segura-Bayona, IRB Barcelona)

Several media have echoed research by IRB Barcelona researcher Travis H. Stracker on the key role of the TLK2 gene for the development of the placenta and for embryo viability in mice.

Published in the journal Cell Death and Differentiation, this finding may be of biomedical relevance. A recent massive genomics study of people with intellectual disabilities performed in the Netherlands points to TLK2 mutations in this population.

Selected media mentions

Link to EFE Futuro

Link to La Vanguardia

Link to El Periódico